( 676 ) 



the test-animals were killed already 5—48 hours after administering 

 the foremen tioned substances. 



Some cavies (experiment n n . 1 — 5) had eaten bread, mixed with 

 soot, Indian ink or carmine. After the dissection of the animals, the 

 lungs showed only the ordinary physiological anthracosis, but car- 

 mine was to be seen neither in the lungs nor in the bronchial glands. 



( >ne of these animals (experiment n°. 4) had evidently aspirated soot, 

 for in many bronchi and corresponding alveolars, foodparticles and 

 soot were distinctly seen in large quantities. 



Also after 'introducing various matters with the catheter into the 

 stomach of rabbits (experiment n c . 6 — 10), aspiration was observed once 

 (experiment n°. 10), whereas among other animals only the normal 

 pigmentation was present. 



In order to prevent aspiration with certainty, tracheotomy was 

 performed with three rabbits and after that a suspension of carmine 

 was brought into the stomach with the catheter (experiment n°. 11 

 —13); for the same purpose among some cavies I injected coloured 

 particles into the distal part of the oesophagus which was nit through 

 and then bound up (experiment n°. 14 — 18). After dissecting no traces 

 of coloured particles were to be found neither in the lungs nor in the 

 bronchial glands. 



Further with differenl cavies the tine particles were directly brought 

 into the intestines after laparotomy (experiment n". 19 — 35). Neither 

 was then any of the coloured matter to be found in the lung-tissue 

 nor in the bronchial glands, whereas everywhere else nothing was 

 to be seen except normal anthracosis in varying intensity. 



Among some experiments I noticed that coloured particles which 

 were injected directly into the intestines, were later on to be found 

 also in the stomach, in the oesophagus and in the pharynx, sometimes 

 in large quantities (experiment n°. 21, 22, 29 and 30). In the phlegm 

 of the trachea the coloured particles could be distinctly seen some- 

 times with the use of the microscope (experiment n°. 21 and 29), 

 whilst once (experiment n°. 29) the easily recognisable ultramarin- 

 grains were to be seen even in the phlegm of the chief bronchi. It 

 is quite probable that the animals in agony had aspirated these sub- 

 stances from the pharynx, for, according to Nenniger 1 ) e. g. bacteria 

 too are often aspirated from the pharynx in agony. 



The question is now, how came the matter from the pharynx 

 into the intestines. Was it by a motion of the fine particles in a 



] ) Zeitschr. f. Hygiene u. Int'ectionskrankheiten, Bd. 38. 



