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young perfon who took the powder, and with the fame regimen. 

 I was not a little furprifed, however, when he informed ms that 

 it operated three times, and that almoft as brifkly as thirty grains 

 of the fame rhubarb had done a few days before, when given in 

 powder. 



Exp. II. At the interval of three days, he took the like 

 quantity of the refiduum of the Englilh rhubarb No. I. This 

 operated three times, and almoft as freely as thirty grains of the 

 powder of the fame No. I. had done before. 



Exp. III. At the like interval he took the refiduum of the 

 Englilh rhubarb No. II. which alfo operated three times. 



Exp. IV. At the farther interval of three days, the refiduum of 

 the Eaft-Indian rhubarb was adminiftered, but without producing 

 any fenfible operation. He experienced no ficknefs, naufea, or 

 griping, from any of the above dofes. The fmall ulcers in his 

 leg had gradually aflumed a better afpeft, and were now entirely 

 healed, though no other medicine had been taken. 



Exp. V. To a healthy perfon, in the prime of life, were 

 given, at due intervals between each dofe, Turkey rhubarb, and 

 Englifh rhubarb No. I. and II. in powder, of each thirty grains. 

 The two former operated only twice; the laft operated three 

 times very brifkly. Each tinged the urine, the Turkey rhubarb 

 moft; No. II. the leaft. 



Exp. VI. In order to determine whether the aftrmgent qua- 

 lity of the rhubarb was intimately connefted with the tinging 

 property, fo as to accompany it in the urinary fecretion, ten 

 drops of the chalybeate folution were added to a wine-glafsful of 

 the tinged urine on the feveral days that the above refpeiftive 

 dofes of rhubarb were taken; but no vifible change of colour 

 epfued. 



Exp. VII. Towards the clofe of the year 1784, a robuft wo- 

 man, aged 46, who had for the laft ten days laboured under an 

 oi)ftinate conftipation of bowels, attended with frequent cojick 



pains. 



