[ 4^9 3 



pains, flatulency, head-ache, and giddinefs, took at my rcquelt 

 of the powder of EngliOi rhubarb No. I. and 11. in dofes of 

 thirty grains each alternately, every other night, till flie had 

 taken fix dofcs. No. I. generally procured three eafy motions ; 

 No. II. feldom occafioned more tJian two evacuations. The 

 fymptoms abated after the firft dofe, and finally difaappeared be- 

 fore (he had taken the fifch, and have never returned fiace, tho» 

 no other remedy was adminiftered. 



, Exp. VJII. Four tanftures were again drawn from the four 

 different kinds of rhubarb, by macerating fixty grains of each in 

 two ounces of proof fpirit in feparate phials for feven days. On 

 filtering the tmdures, and drying the refidua, it was found that 

 the fpirit had extrafted forty grains from the Turkey rhubarb ; 

 thirty-feven grains from the Eaft-Indian ; thirty-two grains from 

 the Englifli rhubarb No. I. ; and thirty-four grains from No. II. 

 The refiduum of each, however, ftill retained a confiderable de- 

 gree of ailringency, as appeared from the inks which they yielded 

 with the chalybeate folution. - The charadters written with them 

 were indeed lefs black than in a former experiment ; thougli fuf- 

 ficiently fo to mark out the aftringent quality. The Tur.key 

 rhubarb give the darkefl fliade ; the Englifh No. II. the lighteft. 



Ex p. IX. To a healthy middle-aged perfon, were given, at 

 fuitable intervals, in a glafs of fpring water, the refidua of each 

 of the tinflures alternately with an equal weight of the different 

 rhubarb in powder; when it w'as again found, that the refidua of 

 each operated very nearly as much as the feveral powders; ex- 

 tept that of the Eaft-Indian, which had no fenfible operation, 

 while the powder of the fame root operated twice. The refidua 

 likewife evidently tinged the urine, and proved diuretic, even be-v 

 fore their cathartic operation commenced. 



Exp. X. Since writing the above, Mr. Thomas Davis, late 

 an ingenious apothecary at Bradford, to whom I had recom- 

 mended fome experiments with Englifh rhubarb No. I. favoured 

 me with the following account :— 



"The 



