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♦' The EngUfh rhubarb greatly exceeded my expeftations ; I 

 gave it to a patient of a weakly habit, and found it operated both 

 by ftool and urine more powerfully than an equal quantity of 

 the Eaft-Indian rhubarb." 



In a fubfequent letter, he adds, " I am now Well convinced 

 that the Englilh rhubarb, after being infufed in boiling water, 

 cold lime water, or reftified fpirits of wine, does not remain an 

 inert mafs deftitute of virtue. I attended to the efFefts of thefe 

 feveral preparations as clofely as my time would admit, and 

 having made the following experiments which you lately fug- 

 gefted, I (hall now mention the refult. 



Exp. XI. " Having infufed one drachm and a half of Eng- 

 lifh rhubarb, in three ounces of boiling water, for twenty-four 

 hours, and having flrained, dried, and pulverized the refiduum, 

 1 gave forty -five grains of it to a poor man in two ounces of pep- 

 permint water; it procured two loofe ftools in about five hours. 

 In the evening he complained of griping pain of his bowels, with 

 giddinefs, and pain of the head and loins, which obliged him at 

 fix o'clock to go to b;d. Thefe fymptoms increafing, I vifited 

 him at nine, and found his pulfe full, and that he had paffed at 

 lead a gallon of pale urine. Next morning I found him perfeftly 

 recovered. 



Exp. XII. After infufmg the fame quantity forty-eight hours 

 in three ounces of re£lified fpirit of wine, I gave the fame perfon, 

 at the interval of three days, fifty-five grains of the refiduum. 

 The urine after the fccond making was very pale, but not in fo 

 large a quantity as after tlie firft dofe. It gave him eight very 

 brifk motions w ithout griping him. 



Exp. XIII. After infufmg the like quantity In three ounces 



of cold lims water, I gave him, at the further interval of two 



days, fifty grains of the refiduum. This procured only two 



ftools, but as much urine as the firft dofe. Before it operated, 



he complained of fevere pain, but it foon went off." Thus far 



my correfpondent.— — ^- 



Remarks, 



