49S ESSAYS and OBSERVATIONS 



tradions will not only be more flowly 

 repeated, bat the pulfe will be full, be^ 

 caufc the ventricles do not contrad till 

 they are much diftended with blood. 

 This win ftili further appear, if we con- 

 fider how remarkably flow and full the 

 pulfe is in an apoplexy, where the fenfi- 

 bility of all the parts and their aptitude 

 for motion are much more impaired than 

 in common fleep ; and how opium, which 

 bccafions fleep, and leflens the fenfe of 

 feeling every where through the body, 

 when given in a large dofe, renders the 

 pulfe uncommonly flow and full. Thus 

 the heart of a frog, into whofe ftomach 

 and guts I had, an hour before, injeded 

 a folution of opium, was obferved to beat 

 near four times flower than ufual ; and 

 the auricle and great veins leading to the 

 keart, were remarkably diftended with 

 blood, as was alfo the ventricle of the 

 heart before every contra6lion. At the 

 fame time the other mufcles of this ani- 

 mal were fo intirely deprived of feeling, 



as 



