1897 THE MICROSCOPE. 85 
The Microscopical Proof of a Curative Process in 
Tuberculosis. 
By CHAS. DENISON, M. D., 
DENYER, COL. 
Tuberculin and antipthisin (Kleb’s) which is considered 
by some (Trudeau and Baldwin) only a modification of it 
has not impressed the medical profession with its great 
worth as a means of treatment, for reasons the profession 
are probably responsible for, though as a diagnostic of 
tuberculosis its position is well recognized by veterinar- 
ians. 
The purpose is to diagnose tuberculosis and differen- 
tiate its varieties by the microscopic examination of the 
blood alone, without the patient being seen. 
It was to apply Dr. Holmes’ method of staining and 
blood examination in order to determine the cell changes 
induced by the reaction to tuberculin, that I asked Dr. 
Holmes to study with me two of my cases some ten weeks 
ago. The results are new, and I am gratified to present 
them in so clear a form, considering the short time the 
study has been in progress. Much eredit is due Dr. Hol- 
mes, for | am unaware that just this method of study 
and comparison has been carried out by any one else. 
Case one was primarily a pulmonary, and afterward a 
surgical tuberculosis affection. 
Case 1—Male, age 38, first seen July 26, 1895: mar-— 
ried; mother had died of consumption; had la grippe two 
years previously, followed by cough, and last winter 
another attack, when he had night sweats. Weight about 
150; not decreased, because of good living and care; only 
slight effect of elevation ; cough not severe ; expectora- 
tion whitish, about one ounce in twenty-four hours and 
containing tubercle bacilli, three to five to field, strepto- 
cocci and diplococci. Some infiltration and dullness at 
left apex, and very slight impairment of respiratory 
