116 The Minnie Anatomy of Two Cases of Cancer. 
tissue, so far as it could be made out, was essentially similar to what 
was observed in the liver. (See Microscopical Section, Nos. 2642 
to 2655.) 
No. 960, Medical Section. The uterus and its appendages. 
Each ovary is transformed into an oval somewhat nodulated scirrhous 
mass, an inch and three-quarters in long diameter. In sections no 
trace of Graafian follicles or ovules could be discerned. The scirr- 
hous mass everywhere consisted of a tissue very similar to that 
above described in the breast. Simply the meshes of the nucleated 
cylinders were longer, so that when the section passed parallel to 
them they could sometimes be traced running parallel to each other 
for some distance ; moreover, the connective-tissue stroma was more 
conspicuously fibrillated than in any of the other growths. (See 
Microscopical Section, Nos. 2449 to 2467.) 
No. 956, Medical Section. The heart. No. 957, Medical Section. 
A portion of the pericardium. On the surface of the heart and of 
the parietal pericardium were a number of flat white thickenings, 
which were at first supposed to be carcinomatous. They proved on 
section to be composed of an imperfectly-fibrillated matrix, in which 
numerous small corpuscles were imbedded, and probably are to be 
referred to some previous inflammatory process, and not to the 
carcinomatous disease. (See Microscopical Section, Nos. 4690 to 
4693.) 
On reviewing this case we cannot fail to be struck first with the 
great similarity of the minute structure of all the morbid growths, 
although seated in quite diverse organs. Everywhere the normal 
tissue characteristic of the part affected appeared to be replaced by 
the morbid product, which was everywhere similar in texture. 
This similarity of texture has long since been frequently ob- 
served in multiple carcinomatous growths and is the anatomical 
basis of the doctrine of a cancerous dyscrasis regarded as the con- 
stitutional cause of the local affections. It will readily be under- 
stood that if we could believe in a special modification of the blood 
giving rise to peculiar organizable exudations, we should expect the 
tissues thence derived to be everywhere characterized by some com- 
mon structural features, the consequence of their common origin. 
Such a view as that of Koester, however, would equally well explain 
the circumstance referred to. For if the nucleated cylinders are, 
everywhere, transformed lymphatics, they must be expected to have 
very many features in common, combined with some minor differ- 
ences in the calibre of the cylinders, the size of their meshes, &c., 
consequent upon the local variations in the character of the finer 
lymphatic nets. 
Koester describes the network of cylinders in epithelial cancer 
as “ cell cylinders ” and was able by silver imbition to map out cell 
