124 PROGKESS OF MICROSCOPICAL SCIENCE. 



it must not be supposed that we have further complaint to make. We 

 have cited all the points to which we object, but not a tittle of those 

 of which we cannot but approve ; and that we think is enough to show 

 what an immensely improved edition is that which has made its ap- 

 pearance under the skilful care of Dr. John Matthews. 



PEOaEESS OF MICEOSCOPICAL SCIENCE. 



The Pathological Changes in Cattle-plague. — Dr. E. Klebs describes 

 the results of his researches in this direction in the ' Wiirtzburg Ver- 

 hand Phys.,' vol. iv., and Dr. Klein embodies them in his report to the 

 ' Medical Eecord ' as follows : — " The epithelium of the summits of 

 the fungiform papillae becomes disintegrated by immigration of micro- 

 cocci from the surface ; the blood-vessels and lymphatics of the mucosa 

 become gradually filled with micrococci ; these latter being regularly 

 distributed through the mucosa, the cells of which commence thereby 

 to proliferate. In the very resistant epithelium of the hooked papillae 

 there appear after a diffuse infiltration with micrococci a system of 

 communicating cavities, which contain at first only lumps of micro- 

 cocci, but afterwards, in consequence of a transudation from the 

 blood-vessels, also serum and lymphoid cells. The ducts of the labial 

 mucous glands become the seat of a very abundant accumulation of 

 micrococci, which probably penetrate into the sui'rounding connective 

 tissue and blood-vessels, thus causing in the former proliferation, in 

 the latter emigration, of the cellular elements. In general the first 

 changes take place in the epithelium of those parts of the mucous 

 membrane of the mouth which are favourable to the adhesion of the 

 food, e. g. the edges of the gums, the summits of the papillae clavatse 

 and circumvallatae, as well as the basis of the hooked papilla, and 

 these changes seem to be produced by the immigration of micro- 

 cocci from the surface ; viz. from the adherent food. In the mucous 

 membrane of the intestine an infiltration with lymphoid cells takes 

 place in the mucosa between the Lieberkiihnian crypts, whereas the 

 sub-mucous tissue and its blood-vessels contain abundant micrococci ; 

 in the latter they may produce even complete obstruction." 



Striated Muscular Fibre. — Singularly enough an immense number 

 of researches has been made on this subject within a comparatively 

 short time, and a great many different observers have been at work on 

 the same siibject. Dr. Klein, however, has gone fully and fairly into 

 the subject in two numbers of the ' Medical Record,' as the following 

 lengthy quotation will show, which deals with the inquiries of Flogel, 

 Merkel, Engleman, and Mr. Schiifer, whose researches we have already 

 described : — 



According to J. H. L. Flogel, in a paper on the striped muscles 

 of mites,* the muscular fibres of the limbs and mouth, as well as those 



* Max Schultze's ' Archiv,' vol. viii., part 1 . 



