i 74 THE MICROSCOPE. 



inating. The vomito negro (black vomit), according to this author, 

 }s due to the presence of these black mycelia; and the blood has not 

 any influence on the color. In urine, he has observed small yellow- 

 ish granules, which give birth to spores. If rabbits or dogs be in- 

 jected with this urine, they exhibit febrile symptoms, with increase 

 of temperature, which last two or three days; and the urine of the 

 animals under experiment presents the same kind of granules as 

 those observed in that of yellow fever patients. Animals which have 

 once been subjected to injection resist the effects of a second. In 

 order to render an animal exempt from yellow fever, it is sufficient 

 to inject into it a small quantity of distilled water containing the 

 specific fungus of the disease. The spores of the peronospora lutea 

 are present in the urine of yellow fever patients for a length of time 

 after their recovery. Their presence, he says, is the reason why 

 such patients are not subject to a second attack. To test the 

 amount of danger of prophylactic injection, he performed it on him- 

 self without any bad results; his urine, however, for some time con- 

 tained the characteristic granules. 



This leads us to republish, in a condensed form, with new plates, 

 Prof. Holland's (of the University of Louisville) article that 

 appeared in our columns four years ago. 



Fig. i represents the deposits from the urine of a white boy, 

 aged fourteen years, who had for several weeks complained of 

 malaise and frequent urination. It was drawn by catheter on the 

 fourth day, after deep pressure above the pubes. He was delirious, 

 and died on the fifth day. The urine contained diffused granular 

 matter and renal tube-casts, highly, moderately, and slightly granu- 

 lar. Some have epithelium embedded, and in various parts of the 

 field are single fat-cells from the urinary passages, which are studded 

 with small fat globules. The urine was acid, lemon yellow, and con- 

 tained bile pigment and one-half albumen. 



Fig. 2 represents the appearance of a copious brownish deposit 

 obtained from the urine of a white man, aged thirty-five, who had 

 been sick of yellow fever four days. He had hemorrhages from 

 various parts, and died on the seventh day. The case was regarded 

 as typical, and the water was passed freely. 



The objects seen are: At the top, a highly granular tube-cast, 

 made probably by degenerated renal epithelium. Such cylinders 

 were quite abundant. At the bottom is a cast of a convoluted tube, 



