REMARKS ON PATHOGENIC BACTERIA. 249 
mention, that is, I succeeded in several cases in checking the pro- 
gress of the morbid process of southern cattle fever, which mainly 
develops in the liver, and (secondarily) in the spleen, by giving 
extraordinarily large doses of chinoidin (amorph. quinin), doses 
amounting to one drachm for every hundred pounds of live weight. 
A very marked reduction of temperature, about four.degrees with- 
in twelve hours, regularly followed, and the disease abated. 
In conclusion, Mr. Presidertt, allow me to say a word in regard 
to the classification of bacteria, schizophytes, or schizomycetes. 
As remarked before, we just stand at the threshold of what may be 
learned in regard to these minute and simple organisms, which will 
probably be considered in the future as a fourth kingdom, already 
named by Haekel, “‘ Protista.” Consequently our present classifica- 
‘tions cannot be expected to be perfect. That of Cohn probably is 
the best, but it, too, can not lay any claim to perfection. So, for 
instance, it seems to me, the genus micrococcus has no real 
foundation, because according to my observations a micrococcus is 
not a perfect or mature bacterium (bacterium used as a generic 
term), but only a transitory or unripe form. Micrococci, wherever 
the conditions are favourable, soon form zoogloea-masses. In these 
zoogloea-masses the single cocci soon become double, form diplo- 
cocci, then the glia breaks, whether on account of a consumption 
or absorption of the viscous mass, which constitutes the glia, by 
the cocci, or whether on account of the-increased bulk of its con- 
tents caused by the growth of the cocci, that is, their change into 
diplococci, I do not know. The diplococci and the yet unchanged 
micrococci become free or gradually separated from the glia, but 
the development or propagation does not cease: on the contrary, 
proceeds with increased rapidity. The single cocci (micrococci), 
or most of them, soon become double and every diplococcus in a 
short time doubles itself at both ends, and forms a small chain, 
first of 4, then of 8, then of 16, etc., links; then the chains, when 
grown to some length, commence to separate, or to break up into 
shorter chains, or even into diplococci, but zever in smaller portions : 
than a double or figure « micrococcus (diplococcus). At least I 
never saw a single micrococcus separate itself from a chain, or from 
a diplococcus, consequently the single micrococci must have a 
different source, and must proceed from so-called lasting spores, 
which sometimes can be found developed among some adiplococct that 
have become separated from a diplococcus chain. Consequently, I 
have come to the conclusion that at least some micrococci— 
whether all the different species of micrococci, I do not know— 
constitute only a transitory form, and therefore have no right to be 
looked upon as the typical form of a genus. 
Mr. President, inasmuch as you asked me to address this learned 
assembly totally unprepared, I hope the latter will treat with 
