37 
with  iodides.  Among  the  pulmonary  pseudo- 
tuberculous  diseases,  there  is  also  the  pa¬ 
rasitic  hemoptysis.  The  examination  of  the 
sputum  establishes  immediately  the  diagno¬ 
sis,  showing  reddish-brown  operculated  eggs 
80-100  micra  long,  40-60  broad.  The  treat¬ 
ment  of  parasitic  hemoptysis  is  purely 
symptomatical.  The  tracheo-bronchial  tubes 
and  even  the  lungs  are  still  affected,  primi¬ 
tively  or  during  the  evolution  of  different 
infections,  by  various  and  sometimes  severe 
affections.  The  minute  discussion  of  the 
inexhaustible  subjects  forming  the  complex, 
known  as  pathology  of  the  respiratory  sys¬ 
tem,  however,  is  not  our  task.  For  distinc¬ 
tion  and  differentiation  we  mentioned  only 
the  capital  points,  which  are  quite  sufficient 
for  those  who  want  to  see.  -  Besides  those 
already  stated,  we  sought  still  for  other  ele¬ 
ments,  to  corroborate  the  results  of  our  stu¬ 
dies.  So  we  recurred  to  the  phenomena  of 
immunity,  in  their  long  and  manifold  se¬ 
quels.  After  examination  by  direct  smears, 
various  stainings  and  fixations,  cultures  in 
Sabonraiid’s  and  Drygalski's  media,  etc., 
after  inoculations  in  guinea-pigs,  rats, 
rabbits  etc.,  minute  clinical  examination, 
careful  exclusion  of  causes  of  error  for  each 
case,  when  the  diagnosis  of  tuberculosis, 
due  to  Oidiu/n  brasiliense  is  almost  certain, 
we  may  still  recur,  as  to  additional  proofs,  to 
the  specific  fixation  test  and  to  intradermo- 
reactions.  We  did  not  try  the  mycotic  cuti- 
reaction  on  account  of  the  almost  unavoida¬ 
ble  causes  of  error,  to  which  such  researches 
are  subjected  in  practice. 
Immunity  reactions. 
The  sporo-aglutination,  to-day  of  cur¬ 
rent  use  in  certain  mycoses  and  of  incontes¬ 
table  value,  did  not  give  us  yet  very  clear 
results.  Be  it  due  to  imperfect  methods  or 
to  difficulties  inherent  to  the  qualities  of  the 
fungus,  this  failure  is  by  itself  worth  men¬ 
tioning.  The  intradermoreaction  for  Oidium 
brasiliense  is  obtained  by  inoculating  sub¬ 
cutaneously  (in  the  derma)  some  drops  of 
an  emulsion  of  the  fungus,  killed  by  heat 
(56o  for  1  hour).  The  vehicle  may  vary.  The 
reaction  is  exclusively  local.  Its  simplicity, 
harmlessness,  and  rapidity  make  it  a  good 
method  for  the  clinical  diagnosis  of  the  spe 
cies.  We  tried  ityin  very  numerous  other  cases 
of  human  disease,  including  tubercular  af¬ 
fections  (due  to  KOCH’s  bacillus),  syphilis 
and  ulcers,  diseases  of  the  digestive  system, 
adenomycosis  etc.  The  reaction  was  always 
negative  in  the  cases,  where  the  Oidium 
was  absent. 
These  results  are  worth  registering,  es¬ 
pecially  in  tuberculous  affections,  due  to 
KOCH’s  bacillus,  and  in  syphilis.  We  also 
applied  it  in  some  cases,  in  which  the  nature 
and  localisation  of  the  lesions  facilitated  or 
contributed  to  the  proliferation  of  other 
fungi,  and  in  cases,  where  the  buccal  florr, 
showed  abundant  forms  of  fungi  of  a  certain 
group. 
Specific  intradermoreactions  in  patients, 
not  suffering  from  oidiosis,  were  seen  only 
once  in  20  observations,  the  reaction  being 
only  feebly  positive.  In  those  of  strong  vita¬ 
lity  the  appearance  of  the  intradermoreaction 
by  Oidium  brasiliense  is  twofold.  In  feeble 
reactions,  there  is  local  redness  after  24  to 
48  hours.  This  redness  is  not  very  accentuated 
and  may  be  slightly  painful  on  pressure  in 
its  center.  On  the  3rd  day  everything  disap¬ 
pears.  In  the  strong  reactions,  belonging  to 
the  second  period  of  the  manifest  disease 
(in  any  form),  the  results  are  different.  After 
20  to  24  hours,  the  place  of  inocu'ation  ap¬ 
peals  intensely  red  and  painful,  either  spon¬ 
taneously  or  on  palpation.  A  slight  promi¬ 
nence  is  noted  in  the  cutaneous  tegument. 
This  may  increase  in  the  following  24  hours 
(see  the  photography),  reaching  the  size  of  a 
lentil.  Around  the  principal  point,  there  is  a 
reddened  halo  of  about  3  cc.  This  aspect  re¬ 
mains  unaltered  for  72  and  up  to  96  hours, 
the  reaction  then  receeding  at  a  varying  rate, 
according  to  the  patient.  After  7  days,  at  most, 
there  remains  only  a  slight  desquamation. 
This  intense  local  reaction  is  not  accompanied 
by  any  other  local  or  general  symptom.  The 
temperature  does  not  exceed  36,9°.  The  pul¬ 
monary  lesions  are  not  modified. 
However,  we  do  not  expect  to  obtain 
