HUMAN PEDIGREES 19 



The next feature in the Pedigree we have to 

 consider in order to deal with it from a Mendelian 

 standpoint is the view we ought to take of the con- 

 dition of members Nos. 1, 2, 8, and 14 in the P genera- 

 tion. These individuals did not attempt to commit 

 suicide, but their degree of melancholia was so great 

 and their general behaviour such that, knowing the 

 family history, their friends thought them safer in 

 an asylum. In 1907 they were free citizens and 

 were still living. In the Pedigree Chart we have 

 indicated them, in the way their relatives and medical 

 advisers apparently viewed them, as insane. If they 

 are to be regarded as potentially afflicted with the 

 family insanity, then they bring the number of insane 

 members too high, if the case is regarded as one of 

 simple Mendelian segregation of insanity and normality. 

 If, however, they are to be regarded as merely 

 extremely melancholic persons, but not insane, then the 

 Mendelian expectation will be 7 -5 of those afflicted and 

 7 -5 of those not afflicted. The result — u'pon this view 

 of the nature of these members — is 6 : 9 respectively. 



(2) A Pedigree of Tuberculosis. 

 The ramily of C. Pedigree Chart 2. 



BY GEO. P. MUDGE. 



The following Family history was brought to my 

 notice, in response to some enquiries which I made, 

 in the early part of this year. The information was 



