150 RRTCHKL : 



In man the symptoms are best made known in referring to 

 one of the two cases reported by McCarthy and Ravenel in 

 1901 : Case No. i. Male, aged five, had been perfectly well 

 up to May 13th, 1901. At that time he was bitten on the 

 cheek by a stray dog. The wound healed and he appeared to 

 be in good health until June 15th (42 days after the bite.) 

 During the night he cried during his sleep. The following day 

 he was up and about, but did not appear to be well . He ate very 

 little during the day. Citrate of potassium was adminis- 

 tered by the mother; free purgation resulted. June i6th, in 

 the evening, he did not appear able to drink, as he asked for 

 water, and then asked to have it taken away after attempting 

 to drink it. June :7th he was admitted to the St. Joseph's 

 Hospital, with temperature loi. He was very much fright- 

 ened, evidently the initiative stage of the disease. He was 

 tested as to his ability to drink, and ever}- time he attempted 

 to swallow there resulted a spasm of the glottis and the 

 muscles of the neck and face. He refused to repeat the first 

 attempt. In attempting to wash him, he became nervous, but 

 was still ver)^ nervous from the tests at swallowing. At 7.30 

 P. M. he succeeded with much difficulty and after persuading, 

 in drinking six ounces of coffee. Marked spasms occurred 

 with each mouthful of the fluid swallowed. Shortly after 

 this general convulsions ensued, the contraction of the legs 

 being most marked. At 11 P. M. the pulse became very 

 rapid, the patient very restless, and in a short time delirium 

 set in. He imagined he saw his father under a sheet, with 

 holes in his eyes. The expression, which from the beginning- 

 was very anxious, now assumed a terrified aspect. At 11.43 

 he was pulseless, did not react to stimuli, and died at 12 A. M. 

 Autopsy showed nothing abnormal. Nervous system exam- 

 ined ; showed changes as seen in rabies. 



As there is no danger from a dog bite if the animal has 

 not rabies, one recognizes the importance of an accurate diag- 

 nosis in each instance. The clinical synijUonis are well 



