THE MICROSCOPE. 13 



(apparently) in some cases so much so as not to be able to differ- 

 entiate it from c. In no case did c. seem to contract as much in 

 proportion as b. although (not measuring) I thought they did some; 

 but was not this merely a change of form without change of density, 

 for a. in fig. 12 became thicker altering the outer form at c. fig. 12. 

 Many of the changes I saw going on when the focus and light were 

 constant. Again by extremely careful manipulation I am convinced 

 that in corpuscles 11 and 12 I saw double contour to an investing 

 membrane or sac. Figs. 11 and 12 I drew three times the diameter 

 seen in hopes to approach the appearance under the microscope in 

 this double contour but have made a failure; in all other respects 

 the drawings of corpuscles 4, (7 contracted state of 4) 

 5, (8 contracted state of 5) 6, 9, 10, 11 and 12 

 give a good representation of how they appeared to "Gray 

 Beard," an appearance totally different in their indications from 

 what I have been taught to believe respecting the structure of the 

 red corpuscle of human blood. Figs. 4, 5, 6, 9, 10, 11 and 12 were 

 the most marked of any of the corpuscles I saw. There were many 

 others giving an intimation of the same appearance, yet there was 

 hot even one crenated corpuscle seen, and very few that were even 

 distorted from circular (outer) conformation. There was only one 

 other seen in position of Fig. 12. Could not find even one white 

 corpuscle, although I searched for them. Am not pathologist 

 enough even to think what it may mean! What does it mean in this 

 instance? 



The mass of the corpuscles impressed me as having less of the 

 bi-concavity than normal. Can it be that this lessening of the con- 

 cavity and change of color (from normal) are in any way associated. 

 I'm inclined to think so, but it leads me into a chemical field not 

 only beyond my expeVimentation, but beyond my pen. 



Corpuscle, Fig. 12, I did not find till after internal contraction 

 had ceased, when it presented a sight which would have astonished 

 any microscopist of the age — a clear view through a corpuscle 

 edgeways showing outer sac of double contour, nucleus, contracted 

 mass around nucleus, leaving a perfectly transparent space between 

 it and the outer sac. I was not in search of light to support any 

 theory, but merely looking to see what I could see, and saw only 

 that which was in direct opposition to what I had been taught, be- 

 lieved, and found endorsed by the mass of my readings on the sub- 



