Progress of Foreign Science. 145 
A disease of the horse, little known, was proper to verify the 
precision of these results. Veterinary surgeons call this disease 
wmmobility; and, in fact, when it is wished to make the animal 
seized with it, fall back, whatever effort be employed, and what- 
ever means be taken, it stands motionless. ‘The forward move- 
ments are, on the contrary, easy, and seem sometimes to occur 
even without the participation of the will. If the inference whick 
I have drawn be exact, the disease ought to consist in a physical 
alteration of the cerebrum, or in some obstruction of the action of 
this organ. I caused to be examined, last month, two horses at- 
tacked with immobility, and the conjecture has been completely 
verified. In both the cerebrum was visibly altered; the cerebel- 
lum, on the contrary, was unaffected. It appears, then, to be de- 
monstrated, that the two opposite motive forces of the cerebrum 
and cerebellum exist in animals, and that, in certain cases, they 
may be withdrawn from the influence of the will. M. Magendie 
relates a case of a man somewhat similarly affected, who was 
cured by some grains of sulphate of quinina.—Ann. de Chim. et de 
Phys. xxiii. 429. 
Prussiate of Iron as a Cure of Intermittents. 
Doctor Zollickoffer, of Baltimore, has employed this substance, 
and his success has been as remarkable as with cinchona.—Journ. 
de Pharm. July, 1823. 
Injection of a Solution of Opium into the Veins of an Hysterical 
Patient. By Charles W. Coindet. 
This experiment was made at Edinburgh, and the result was 
such as to deter any young physiologist from repeating it in hys- 
teria. The patient was seized with violent spasms, constituting a 
case of idiopathic tetanus. They commenced very regularly by 
attacks of emprosthotonos, the head frequently striking the knees 
with force, Opisthotonos succeeded; the body took the form of 
a bow, and rested only on the heels and occiput. All the muscles 
of the body participated in this state of painful tension, which, one 
time, lasted twenty-seven minutes. The respiration was performed 
with difficulty, the pulsations of the heart became feeble and ir- 
regular, and the young girl (fourteen years of age), was threatened 
with suffocation. This horrible agony was succeeded by some 
convulsions of pleurosthotonos, which terminated the paroxysm. 
Dr. Coindet dissolved a scruple of common opium in an ounce of 
distilled water, heated to the temperature of 80° cent. At half- 
past seven in the evening he began the injection, assisted by his 
friends MM. Hercy and Lucius O’Brien. He made an opening in 
the right basilical vein, with an ordinary lancet as for blood let- 
Vor, XVII. L 
