202 THE MICROSCOPE. 
dissected and demonstrated by my highly esteemed teacher, 
Prof. Dr. von Recklinghausen. In this instance it appeared 
that the entire gland, together with its capsule, was calcified 
an toto, and this mass had penetrated the left principal bronchus, 
to the walls of which it was still somewhat firmly adherent. 
Chemical investigations showed that this mass consisted, to a large 
degree, of carbonate of lime, gelatin-producing substance, and a 
trace of sulphuric acid. The local changes resulting from the 
anthracotic indurations of the lymphatic glands are frequent and 
manifold. They have recently been most elaborately described by 
Zenker, (“Handbuch der Pathologie,” VII, 1, 2, Auflage, 1871, 
Anhang, page 66), and by Eternot (Recherches sur les affections 
chroniques des ganglions tracheo-bronchiques et les suites de ces 
affections, Genf, 1879); and by Oekonomides (Dissertation iiber die 
chronische Bronchial-Lymphdriisen Affection und ihre Folgen, 
Basel, 1852). From these communications the following is deduced: 
If the chronic inflammatory process, adenitis and peri-adenitis, 
continues, it will not remain confined by adhesions with the neigh- 
boring organs, such as the bronchia, arteries, veins, lymphatic 
vessels, or with the cesophagus and the trachea, etc., etc., but may, 
on the one hand, result in dilatation of these organs by retraction, or 
on the other hand, in a contraction by compression. Further, 
Weigert and Roth have asserted that not only the walls of the 
pulmonary vessels, or bronchus, may become necrosed and break 
down, but finally become perforated,* whereby the anthracotic 
pigment may enter the blood directly, as it may on the other hand 
enter the breathing passages, but that such masses may be conveyed 
into and carried through the blood by means of the bronchial vessels 
(arteries and veins) which run along the bronchi and supply them 
with blood. 
Here consequently lies the real etiological moment for the 
transportation of anthracotic pigment (coal dust) into the various 
organs, especially the liver, spleen and kidneys, and also into the 
periportal and mesenteric-lymphatic glands, even into the marrow of 
the bone, by means of the arterial blood-vessels. This process may 
well be termed “Coal-dust or anthracotic metastasis,’ as Roth 
proposed. 
The occurrence of this coal-dust metastasis in the liver and 
spleen is, according to the most recent investigation, by no means 
infrequent; eleven cases of this kind in one month were investigated 
* At the site where this chronic slaty indurated Lymphatic gland lies in contact with 
a blood vessel or bronchus. 
