TmO IV OIM'KliK.NCK INTKIlNATluN AI.K llK (.KM'TInl K. 



In anollier daugliter of lliis womaii llic (issilicil ion nf llic cartilage lias alrcadv 

 occiired in tho (irsl fingor altlioiii^li llu' diihl is uiiiv 1' vcars old. 



Fi-. !t. — Itniiingi-apli i>l li.iiul ni Lim N' -Jl >li,,«ii 

 iiCiiid |iliiil;iii\ rxi|.|il jii Mil' iiiiilillr 11 



llIlM'lllT i.r r|H|ll 



i'<.'iiiil lliiiiiili. 



Tlius il a])|)ears clear llial Ihe 7i"' Inclor coiircriioil in lli(> prodnclion uf 

 i^liorloning ol' lliis middle plialanx is llic prenialiirc ossification ol' llic carlilagc 

 wliich intervenes bctween tlie shal't of llie bono and ils epiphysis. 



The essenlial feature of Ihe alinoi-nialily in iV" I fnniily was slated to be 

 « an absence of Ihe epiphysis al the base of Ihr 'i"' plialanx wilh subséquent 

 anicylosis of the 2°'' to the firsl phahinx. so llial in llic preseni lamily ^ve hâve 

 an abnormalily which is essenlially tiic sanic developmenlally. but >l(i|)ping 

 shorl of ankylosis. 



The second phalanx in llie middle finger is h-ss alIVcIcd Ihan in (lie ollicrs. 

 and lliis was aiso a chaiaclerislic of N" I fauiiiy. 



The second plialanx in Ihe Ihunib dilTers in the Uvo faniilies : in N" I i'aniily 

 the basai epiphysis was absent, but in Ihis family il is présent. 



The locs seem lo be practically idenlical in llie Iwo families. for in bdlli 

 there is an absence of the middie-phalanx-opiphysis, and in Ihe adnlls llieic 



