THE MICROSCOPE. 193 



protruding portion in a kind of stream. Aside from this motion 

 the granules were usually still. Occasionally, however, they had an 

 independent motion, like the motions of the granules in the pus 

 corpuscle before described. I have watched one of the granules 

 move for a considerable distance through the corpuscle; the other 

 granules at this time were vibrating uneasily like individual bees 

 in a swarm. The corpuscle itself, with the exception of an almost 

 imperceptible vibrating movement, remained still. 



These corpuscles usually had one or more places destitute of 

 granules, which resembled nuclei. The spots did not stain with 

 carmine, and were unmistakable depressions. They seemed to me, 

 therefore, to be places free from granules, rather than nuclei. Their 

 floor showed a slightly uneven surface. 



I studied these bodies for about two weeks, the time of the 

 absence of the granules from the blood. After a time the granules 

 began to return. At first they were of a low refractive inde.x, and 

 stained faintly, gradually they assumed their usual appearance. 



About the time of the re-appearance of the granules, I noticed 

 a change in the granular corpuscles. They stained more readily and 

 more deeply with carmine than ever before; the places destitute of 

 granules became larger and more numerous, and I began to see ap- 

 pearances as though granules were leaving them. On two occasions 

 I saw bodies which presented all the appearances of the other gran- 

 ular corpuscles except that the nuclear-like space had enlarged to 

 such an extent that the body was nearly destitute of granules. Many 

 granules were seen in the act of passing out from the corpuscles, 

 and many were seen near the corpuscles as though they had just 

 left them. 



The conclusion from these facts seems to me to be warranted, 

 that the granular corpuscles, at least, are composed of minute round 

 bodies held in a stroma, and that, possibly, they may be the source 

 of the granules found in the blood. — Dr. Lester Curtis in Proceed- 

 ings of American Society of Microscopists. 



