254 H. M. WOODCOCK. 



of a Trypanosorae. Besides this^ Scliaudinn lias since also 

 noticed nuclear dimorphism (i. e. the presence of a larger and 

 a smaller nuclear body) in typical endoglobular individuals of 

 P. canis (cp. P. donovaui below^ p. 260) ; and Kossel and 

 Weber on re-staining and re-examining smears of the intestinal 

 contents of ticks which had fed upon cattle suffering from 

 piroplasmosis came across similar forms. 



Lastly, the instances where authors mention the association, 

 concurrently, of Trypanosomes with either Avian malarial 

 parasites, Piroplasmata, or Hcemogregarines are too 

 numerous to specify (see below in Systematic). Of course, 

 in many cases, this may reasonably be set down as a mere 

 coincidence; it would be unduly straining that explanation, 

 however, to suppose that it is of universal application. 



Section X. The "Leishman-Donovan-Wkight"^ Bodies. 



We may now consider, in some detail, the peculiar para- 

 sites which are generally held to be the cause of certain 

 tropical fevers, particularly prevalent throughout Indo- 

 Burmah, though not, apparently, by any means restricted to 

 that region. These diseases, characterised by irregular 

 pyrexia, splenomegaly and cachexia,^ are known by various 

 names (e.g., Dum-dum fever, Kala-azar, tropical spleno- 

 megaly, etc.) according to the slightly different features 

 and circumstances attending their occurrence in different 

 cases. These varieties are, however, most likely, all due to 

 one and the same specific form of parasite. Moreover, 

 organisms very similar to these parasites (morphologically, 

 indeed, the two sorts appear hardly distinguishable) are found 

 in certain superficial sores or ulcers, to which people in various 



' In order not to injure tiie delicate suscciitibilities of uiodical investi- 

 gators, wliere priority rights arc concerned (vide tlie pages of the 'Lancet' 

 and 'B. JNl. J.' during tlie hist few years with reference to the discovery of 

 parasites in tropical diseases!), the fullest possible title is conferred for the 

 nonce upon these unhappy parasites. 



^ Otlier prominent symptoms in different cases are ulceration of the 

 intestine, cjudema of the feet, and increase in pigmentation of the skin. 



