On the Fluctuations in the Number of лvhite Blood Corpuscles etc. 73 



J. L. L. 



IX— XI06 I1I07 VIII07 XI(06 11/07 



Polynuclear leuc. . 73-9 "/o (741) 60 1 ^'/o 621 ^'z о 818 »/о 702 "/о 



Large mononuc. — 64 - 138 - 10*9 - 52 - 97 - 



Small mononuc— 193- 260- 26 9- 124- 201- 



Eosinophile — 0*4 - (0-2) 01 - 01 - Об - 00 - 



No. of preparations 16 2 7 4 14 



All the samples were drawn in the morning when fasting. In 

 each preparation 400 areas were counted, the preparations being all 

 examined as far as possible in the same manner. The average 

 number of leucocytes in each preparation was 197; the total num- 

 ber of leucocytes counted was thus ca. 8500. 



If we only consider the two main groups, mononuclear and 

 polynuclear cells, we readily see that a relative increase of the first 

 occurs during the dark period, an increase which in both cases 

 amounts to ca. 12 ^'/o notwithstanding individual differences. Bruhn- 

 FÅHRÆUS^ is of the opinion from Jolly's investigations, that the 

 error in the determination of the relative number of 2 forms of 

 leucocytes does not exceed 4 "o, when at least 300 cells are counted. 

 Even with the admitted limitations of my material I think we may 

 therefore conclude, that the increase noted in the number of the 

 mononuclear cells in winter-time is real. The following rounded 

 percentages will show the comparison more clearly. 



Autumn Spring 



Nevertheless the available data are as yet too few and too much 

 subject to chance to permit of forming an approximately reliable 

 picture of the nature and extent of the variations described here. 



Some few observations on the numerical proportions of the 

 erythrocytes may be added here. 



For the work of counting I used, as already mentioned, Breuer's 

 measuring cells with 105 times magnification. In each case I counted 

 2 — 300 blood corpuscles. The quotient is 25,000. All the samples 

 of blood were drawn in the morning while fasting. 



1 L с p. 22. 



