16 S. E. Henschen, 



Amongst the remaining ganglion cells none were quite normal; 

 they were rounded and had lost most of their processes, were more or 

 less diminished, some in a high degree; the contents of the cells were 

 more or less transformed to a granular yellow or yellowish brown mass 

 and the cell nuclei were also changed or had disappeared. In the proto- 

 plasm leucocytes and vacuoles were sometimes met with, and vacuoles; 

 these latter writers regard as a sure sign of a pathological change. Fi- 

 nally the larger vessels were strongly injected. 



An extensive and distinct degeneration of nerve fibres was found 

 in nervi radiales and peronei, which was of varying degree in different 

 parts. Normal as well regenerated fibres were met with by the side of 

 fully degenerated. 



If we now compare the above mentioned changes with those I 

 found in my case the agreement is stricking. 



Unfortunately I had not access tho the more peripheral nerves 

 but the examination of the nerve roots was sufficiently exact and convin- 

 cing. Part of the nerve fibres were quite normal. Their medullary sheaths 

 being well coloured with Weigert's hematoxyline others were in a condi- 

 tion of more or less well-marked degeneration. 



In several, such as for instance the sacral nerves, no distinct co- 

 louring of the marrow sheaths of the nerve fibres could be perceived. 

 In the medulla analogous circumstances were found with those of the 

 Russian Doctors' case. The ganglion cells were reduced in number and 

 most of those remaining were changed. Thev were more or less dimi- 

 nished in size; in the greater number no process was left; many were 

 reduced to small rounded masses with granular contents. (Fig. 4.) In 

 the periphery or other part of the cell-substance, some were unusually 

 translucent, a change which corresponds to the partial change of the 

 protoplasm which Erlicki and Rybalkin speak of in their case. 



These small atrophic cells sometimes showed no signe of nuclei. 



But there was also an interesting and unusual change namely a 

 hemorrhage in the lumbar cord. This was only seen in the grey substance 

 of the left horn which through hemorrhage had become drawn out and 

 deformed and pressed to the periphery of the spinal cord. The hemorr- 

 hage measured about 1 cm. in height and 1 mm. in transsection. The 

 fibres around the hemorrhage were partly destroyed and the ganglion 

 cells in the neighbourhood had evidently suffered from the presence of 

 the extravasated blood. 



