486 REPORT OF THE COMJIISSIOSTER OF AGRICULTURE. 



All tlic lymphatic glnnds in the tlsoracic cavity were of a very dark-red 

 color. On section tliis color was foiiiid tbroueiiout tbo ^laud and a 

 lar.iio anionnt of dnrk-colored blood AoavcmI from the exit surface. 



Tlio^lymphatic glands about the sloinaeli and a!on<^ the entire extent 

 of the nieso-colou were OTilarged, dark i)iiii)lish, similra' in appearance 

 to those of the thorax. Thot^e of tlie colon resembled dark-red beans in 

 size and color. Tlie glands of the mesentery were enlargetl, the cortex 

 reddened, medullary substance slightly- so. The mucous membrane of 

 the stomach was studded with red points near -the lesser curvature. 

 In a few. places hemorrhages had occurred. The clots, when judled 

 away, revealed ])atches thickly covered with ecchyrnoses. The small 

 intestine in general did not exhibit any signs of inllaramation, as the 

 membrane was quite ])ale. But hero and there red points and larger 

 patches of extravasation were found. The large intestine, distended 

 with food, was the seat of the most extensive lesions. The entire mu- 

 cosa was thickly dotted with ecchyinoses varying in size from points to 

 large i)urplish patches. In the I'cctum small red })atches, when examined 

 with a lens, were found to consist of a network of injected vessels. 

 Among the contents of the large intestine, aboui: 10 inches from the 

 ilco-caical valve, a black mass as large as a man's fist was found, which 

 was made up of feces enveloi)ed in a thick layer of clotted blood. Jn 

 the subperitoneal tissue near the ce])halic border of each kidney there 

 was an eccliymosis about 1 inch in diameter. In one kidney a papilla 

 contained several snmll ecchyrnoses. 



This atiimnl was free from intestinal worms, differing in this respect 

 from the majority of those which were examined about the same time. 

 The animal had snccuml)ed to tlu; first onset of a very virulent attack 

 of swine plague, so that ulceration had not yet begun in the large intes- 

 tine. 



Pig No. 7G, an adult animal, is still alive (February, 18SG), and to all 

 appearances well. 



Thus three of the five animals which had been vaccinated died of swine 

 plague, and, moieover, in the. early stages of the disease. One of them, 

 pig 'JJl, just described, had bei>n in excellent condition and was compa- 

 ratively tree from parasites. Lleuce any protection from the American 

 swine plague conferred by vaccination was out of the question. 



Moreover, in these cases great care was bestowed on the examination 

 of cover-glasses of the spleen, of the various exudates, and blood from 

 the heart. In none of them could the delicate bacilli of rouget be de- 

 tected. We had suflicieiitly familiarized ourselves with their appear- 

 ance in the vaccines, in cover glass preparations of the organs of mice 

 inoculated therewith, and in cultures in liquid and solid media, sO as to 

 exclude any errors of observation. We are enabled to say that wo could 

 not detect them by means deemed sufficient by Ji^uropean investigators. 

 We claim, from oui' <twn investig;itions, that the disease prevalent in 

 the East, and [)robably over the entire country, is ditlerent from the 

 disease called rotiget. The above experiments with Pasteur's vaccine 

 do not, in our opinion, therefore, disprove the i)rotective power of Pas- 

 teur's vaccine over rouget, but simply shov,- that the vaccine for one dis- 

 ease will not i)rotect agiiiiist another. 



CONCLUSION OF THE INVESTICrATIOKS CONCERNING THE CAUSE OF 

 A31EK1CAN SWINE PLAGUE. 



The two animals whi(;h infected (lie \ ai'cinatecl jiigs, as described in 

 the preceding pages, deserve our atteutiou more particularly, since they 



