291 
SEGREGATION AND RECOMBINATION OF THE GENES FOR TINGED, 
BLOOD, BUFF, AND CORAL IN DROSOPHILA MELANOGASTER. 
Roscor R. Hype. 
From the Department of Immunology, School of Hygiene and Public 
Health, Johns Hopkins University, Baltimore. 
Contents. 
‘1. Linkage of buff and tinged. 
(a) Buff 2 by tinged. 
(b) Buff & by tinged @. 
Linkage of buff and blood. 
(a) Buff 2 by blood %. 
(b) Buff # by blood ¢. 
Linkage of coral and tinged. 
Te) 
aC} 
ee) 
(a) Coral 9 by tinged 3. 
(b) Coral & by tinged @. 
4. Linkage of coral and blood. 
(a) Coral 2 by blood’. 
(b) Coral @ by blood @. 
Linkage of coral and buff. 
(a) Coral 9 by buff. 
(b) Coral & by buff @. 
6. Linkage of tinged and blood. 
(a) Tinged 2 by blood &. 
(b) Tinged & by blood 9. 
Linkage of coral and eosin. 
Ol 
=I 
(a) Eosin @ by coral <. 
(b) Eosin o by coral @. 
8. Summary. 
9. Literature. 
In a previous paper I reported the origin of blood and tinged, two. sex- 
linked eye mutants in Drosophila. Both mutants gave complete linkage 
with white, eosin and cherry and consequently formed with the red of the 
wild type a sextuple system of multiple allelomorphs. Safir and Lance- 
field later reported buff and coral, two other members of this system, as 
shown by their linkage to white. T. H. Morgan has kindly supplied me 
with stocks of buff and coral and this paper records the combinations made 
with these two stocks to my stocks of blood and tinged. The results of 
these erosses bear out the expectation that, since blood and tinged are 
allelomorphie to white and buff and coral are allelomorphic to white, the 
mutants buff, coral, tinged and blood should show allelomorphism to each 
other. 
The evidence from such a system is significant as it bears on the nature 
of the change that takes place in the chromosomes of mutant stocks. If the 
different mutants are a result of losses of materials that lie at different 
levels on the sex-chromosome, then: the wild type eye should result in the 
daughters on crossing any two of these mutants, since the daughter receives 
two sex-chromosomes and each would restore the missing allelomorph of the 
other. As a matter of fact the daughters from all combinations are com- 
