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DISEASES OF SWINE AND OTHER ANIMALS. 435 
in Rowan, Mecklenburg, Lincoln, Gaston, and AJamance, in the central 
belt, and particular inquiries were made of those who had observed it 
in the counties bordering on the coast. Several counties not enumera- 
ted above were visited, but I was not successful im finding infected 
localities. My greatest regret is that I was not able to make personal 
observations in every part of the State. | 
In each of the counties mentioned a considerable number of herds 
were visited and examined, and without exception the living animals 
presented similar symptoms, and the dead ones showed similar changes 
in the different organs of the body. Slight variations were of course 
observed, as is always the case in any disease, but these were as great 
between different individuals of the same herd, sick at the same time, 
as between different herds, even in different counties. And, what is of 
great importance, i did not find ‘a single case in which it could possibly 
be supposed that death resulted from a local disease; but in every 
case a variety of organs, belonging to different apparatus, were found 
‘diseased ; the blood often showed marked changes; there were extrava- 
gations in various parts of the body, and always inflammation of the 
lungs and large intestines, generally, also, of the heart, and often of the 
eyes; the skin, too, was often plainly affected, and the temperature was 
found to be increased before any other symptoms of disease were in the 
least apparent. 
Considering all these facts, there can be no doubt that these animals 
all died of a general disease—a disease not caused by changes in any 
single organ; but, on the contrary, a disease which caused the various 
_ organic changes observed. Again, from the similarity of symptoms in 
all these cases which I saw, and in those reported to me fgom other 
parts of the State, and from the correspondence in post-mortem appear- 
ances, there can scarcely remain a shadow of doubt that the great mass 
of the hogs dying in North Carolina are affected by one and the same 
disease. 
SYMPTOMS. 
An increase of temperature precedes for an undetermined and prob- 
ably variable length of time the appearance of: all other symptoms. 
In one lot of seven ten-months-old pigs, only one of which showed symp- 
toms of disease, the six remaining had a temperature varying from 
103.6° I. to 106° F., and this temperature was preserved unaltered for 
six days, with no other changes in the condition of the animals than 
increased dullness of the eyes, a general unthrifty condition and a disin- 
clination to search for food, although the appetite was still good. The 
pig first affected died about this time, and a post-mortem examination 
left no doubt of the disease. 
In another lot of ten three-months-old pigs, but one of which was 
plainly sick, six had a temperature ranging from 1044° F. to 107° F.; 
with one this was 1034° F., with two 101° F. and 102° respectively, while 
. with the sick one it reached 107.49 F. 
In a herd of twelve, from which one had just died, and one was plainly 
sick, four others showed a temperature from 103$° F. to 107° F, 
In a lot of fourteen animals, one had died, one was plainly sick, and 
three others had a temperature from 103° F. to 104° F. 
Of five pigs, one had just died, three had a temperature or 105° F, to 
106° F*., and the remaining one 103° F. 
, Of eleven hogs, two had died; one was plainly sick, and five had a 
temperature ranging from 103° F. to 106° F., 
From these and similar cases it has seemed probable that a high tem- 
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