466 REPORT OF THE COMMISSIONER OF AGRICULTURE. 
which also undergo the same metamorphosis as the first one. Hence 
it happens very frequently that farcy boils and ulcers make their ap- 
pearance in rows somewhat resembling strings of beads, which consti- 
tutes one of the characteristics of the disease. A little later the nearest 
lymphatic glands, too, commence to swell and to be changed to hard 
apd more or less paintul farey-buboes. ‘The circulation or the current of 
lymph in the lymphatics of such a swelled gland or glands becomes 
interrupted, and in consequence cedematous swellings make their ap- 
pearance in the parts in which such an interruption has been effected, 
usually in aleg. The swelling of the lymphatics and of the lymphatic 
glands, the lymphatic abscesses, and the appearance cf cedemata have 
led to mistakes; an inflammation of the lymphatics has been supposed 
to constitute the primary and the production of farcy-ulcers a second- 
ary morbid process. Sometimes, it is true, itis rather difficult to find 
the primary boils or ulcers from which the morbid process has spread, 
The comparatively rapid dissemination of the glanders-virus through 
the lymphaiics in the loose subeutaneous connective tissue explains why 
farcy usually spreads sooner over the whole body, and becomes fatal 
in much less time than either pulmonal or nasal glanders. 
The products of the glanders-process, however, do not always present 
themselves as distinctly limited growths in form of nodules, tubercles, 
tumors, and boils. The morbid products in certain cases, especially in 
such in which an inflammatory exudation is taking place in the same 
parts in which the glanders-process has its seat, become diffuse, and the 
glanders-cells almost as soon as produced are carried off by the exuda- 
tion. Gerlach discriminates two forms of diffuse glanders, viz., glan- 
ders-catarrh and diffuse production of glanders-ceils in the mucous 
membranes. 
1. Glanders-catavrh.—lf the glanders-process makes its appearance in 
a mucous membrane, the first morbid changes and symptoms are always 
those of glanders, blended with a catarrhal affection. Consequently the 
first stage of nasal glanders may appropriately be called a “ glanders- 
eatarrh,” and may under favorabie circumstances exist almost unchanged 
for a long time without being attended by any other characteristic symp- 
toms except perliaps some swelling of the submaxillary lymphatic glands 
(so-called nasal gleet). Afterward, in a more advanced stage of the dis- 
ease, more characteristic morbid changes make their appearance, but the 
catarrhal discharge from the nose remains. In glanders-catarrh the se- 
cretions of the nasal mucous membrane differ only in so far from those 
observed in a common catarrh as they present frequently a greenish or 
green-yellowish color, and contain very soon epithelium-scales and small, 
round glanders-cells similar to matter-corpuscles. With the appearance 
of the epithelium débris, however, the somewhat characteristic greenish 
color usually disappears. The glanders-cells have their source in the 
epithelium-producing layer of the mucosa, and develop from epithelum- 
cells, but are carried off or washed away by the fluid exudations. Still 
the discharge itself, although containing glanders-cells, offers no charac- 
teristic of great diagnostic value except its infectiousness, which exists 
from the very beginning. The microscope reveals no essential differ- 
ences, neither between the nasal discharges in glanders and in catarrh 
nor between farcy matter and common pus. 
2. Diffuse production of glanders-cells in the mucous membrane.—The 
glanders-cells are not produced in certain limited spots or nests, but in 
diffusion over large parts of the mucous membrane. ‘The latter appears 
swelled and loosened in its tissue, and contains larger or smaller num- 
bers of round glanders-cells of different size. Afterwards an exuberant 
