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BUREAU OF ANIMAL INDUSTRY. 497 
The ileo-czecal valve is almost completely surfounded by ulceration, the base of 
the ulcers being blackish, and the mucosa much puckered. The colon is bright 
red, dotted with darker points,and covered with small ulcerations, circular as if 
punched out. The base of the ulcers is concealed by a creamy mass, the border 
slightly thickened and intensely reddened. In some places the ulcers number five 
or six toa square inch. Besides these small ulcers there are several about one-half 
inch across, resembling the ragged ulceration in the cecum. The contents of in- 
testine resemble lumps of sand and mud, some extremely hard. Sections through 
a few of the small circular ulcers show that they have arisen around the mouths 
of mucous glands. 
On opening thorax, lungs collapse. Slight fibrous adhesion of right lung to tho- 
racic wall near diaphragm. In each lung the cephalic, ventral, and a small portion 
of the principal lobe, as well as the small azygos lobe, solidified. The hepatized 
portions are bright red, dotted with very minute closely-set, grayish spots, well shown 
in Fig. 2, Plate III. Examined witha lens these spots have a nebulous appearance. 
Onsection this same mottled appearance. A few lobules and groups of lobules are 
converted into greenish-yellow, consistent, cheesy masses. Trachea and larger 
bronchi filled with whitish foam. The smaller bronchi clogged with viscid mucus 
inclosing air bubbles. Cover-glass preparations of alveolar exudate contained cocci, 
of the spleen no bacteria of any kind. Cultures from the surface of the pleura re- 
mained sterile; a liquid culture from the spleen contained three or four forms of 
bacteria. One of these was evidently the microbe found in former cases. A second 
form, a motile bacillus, isolated from this culture with the aid of gelatine plates, re- 
sembled the bacterium of hog cholera in some features, differing from it in others. 
Without giving these, suffice it to say that a rabbit inoculated subcutaneously 
with one-third’s liquid culture was killed in ten days. The lesion was purely 
local; extensive suppuration of the connection tissue of the inoculated thigh. The 
lymphatic glands of axilla onthe same side enlarged, one of them hemorrhagic 
throughout. The internal organs were normal; no evidence of those lesions always 
following inoculation with hog cholera bacteria. 
March 8 a rabbit was inoculated by pricking both ears with a lancet and insert- 
ing into the wound some of the alveolar exudate from the solidified lung tissue. No 
result. Another rabbit was inoculated with the same lung tissue a week later, 
which had been meanwhile kept in the refrigerator. A small bit of lung tis- 
sue was placed beneath the skin of the thigh and the wound closed with a stitch. 
It was killed a week later, though apparently well. A large mass of cheesy pus 
was found at the place of inoculation in the subcutis. Internal organs normal. 
Two mice were inoculated March 8 by placing bits of lung tissue beneath the skin 
at the root of the tail. They died March 13 and 14, respectively. In the heart’s 
blood of both the characteristic bacteria found hitherto, and showing the polar 
stain very clearly, were found in large numbers. Cultures therefrom corroborated 
the microscopic examination. <A table giving the inoculations is appended: 
Pig No. 408, died March 5. 
lung tissue spleen 
plate cult. 
rabbit (ear) March 8, rabbit (thigh) 2 mice March 8, 
no effect March 14, died March 13, 14 b.i. cult, 
i} motile baccillus 
local suppuration swine plague 
bacteria i rabbit March 15, 
killed March 25 
(local suppuration 
only) 
Another pig (No. 409) had been with Nos. 405 and 406 before January 81. Since 
February 1 this animal began to fail. It became emaciated and weak, diarrhea 
set in, a cough was heard when the animal was incited to move. It died March 20. 
Body very thin; skin of ventral aspect coveréd with elevated brownish scales one- 
eighth to one-fourth inch in diameter, easily torn away, and involving only the epi- 
dermis. Petechiz had been observed in the same situation during life ; superficial 
inguinals considerably tumefied, of a mottled, pale-red color. Digestive tract.— 
Stomach distended with food, cardiac expansion softened and apparently macer- 
AG 87 2 
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