498 REPORT OF THE COMMISSIONER OF AGRICULTURE, 
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ated, In the large intestine the riucosa was roughened and covered with pigment «f 
spots 1" to 2™™ diameter, giving the whole membrane a dark appearance. In the 
blind end of the caecum and in several of the saccular dilatations of the colon the 
mucous membrane is superficially eroded, giving rise to circular, shallow ulcers cov- 
ered with a whitish deposit. The lings were extensively hepatized. The solidified 
portions involved the same régions as those heretofore described—cephalic and ven- 
tral lobes and the ventral portions of principal lobes. Only a small area of the 
principal lobe presents the bright red ground mottled with grayish points. The re- 
mainder of the solidified lung tissue is of a uniform greenish, waxy tint, both on 
surface and section; the bronchi plugged with mucus. In those portions of the 
principal lobe which appear normal are scattered groups of hepatized lobules. 
Cover-glass preparations from the diseased regions of older date show chiefly pus 
corpuscles with irregular fragmentary nucleus staining well in methylene blue. 
On one cover giass was found a large colony of minute bacteria resembling those of 
swine plague. 
In sections from the hepatized lobes the alveoli were found, as usual, filled with 
cellular elements. Among these chains of streptococci, consisting of at least 15 to 
30 cocci, were found. In some alveoli only a few were present, in others a consid- ~ 
erable number of interlacing chains could be seen, This strepogoccus, which stains 
very well, according to Gram, will receive more attention later on. No groups of 
cocci resembling those of the swine plague bacteria could be found in the few sec- 
tions examined. 
Cultures from spleen and liver were found to contain several kinds of bacteria. 
A tube culture in gelatine of heart’s blood remained permanently free from bac- 
terial growth. 
From a cheesy mass in the lungs a large white rabbit was inoculated in both ears. 
On the following day both were swollen, red, and drooping back, A few days later 
they were again normal, and although rather quiet and stupid it seemed well. On 
the eighth day it was found dead. : 
Slight swelling about lancet puncture on which there is some dried blood. Har 
otherwise normal, a few strings of fibrine on intestines, spleen enormously enlarged. 
Liver dotted with areas of coagulation necrosis 1™™ to2™™ across. Extensive pericar- 
ditis, the two layers of the pericardium firmly adherent. Pleuritis on both sides. 
The lesions were those caused by hog cholera bacteria,and these microbes were 
found in large number in spleen and liver. Only a few in the pericardial exudate, 
none in biood. Gelatine cultures of spleen and liver and three beef infusion cult- 
ures of blood from the heart contained the motile hog cholera bacteria only. 
Pig No. 409, died March 20. 
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lung lung tissue 
mouse ear of rabbit March 22 
(no result) died March 30 . 
cultures contain only 
hog cholera bacteria 
Another animal (No. 410) from the same farm and herd was attacked with a severe 
skin disease, in which a large area of the skin of the back came away as a slough, 
exposing the muscular tissue beneath. The animal became reduced and was found 
dead March 29. 
The ventral aspect of the body and limbs covered with round, slightly-raised 
scabs, about one-fourth inch in diameter, with bluish-red border. The scab, con- 
sisting merely of epidermis easily torn away, covers a deep-red surface. The ex- 
tensive soya on the back have already been mentioned. Stomach filled with a 
turbid liquid, the membrane of fundus reddened and covered with tenacious mucus, 
which it is almost impossible to scrape away. Mucosa of large intentines of a deep 
red throughout made up of crowded bright red points. No ulceration. Lungs not 
collapsed; left hypostatic. Both principal lobes oedematous; cephalic half of right 
lung emphysematous. Hepatization involves, in the right lung, only the extreme 
tip of cephalic lobe, one-half of ventral lobe, and the ventro-cephalic corner of 
principal lobe; in the left lung only a few lobules of the ventral lobe. The small 
median {az~G08) lobe is solidified along the border in several places. Right heart 
