- 
500 REPORT OF THE COMMISSIONER OF AGRICULTURE. am 
Pig No. 359, died March 24. 
7 
pleural exudate spleen cults. 
b.i. cult. swine plague bacteria 
chromogene 
rabbit (subcutis) March 25 rabbit (subcutis) March 25 
died March 28 died March 26 
(swine plague) (swine pax ) 
gel. cult. (iver) b. i. cult. blood 
b.i. cult. April 2 
2 rabbits (ear) April 4 
died April 7,8 
(swine plague) 
No. 360 was exposed February 18 with pig No. 359, just described. After one 
month of exposure it became very weak and emaciated and kept on failing until it 
was found dead April 6. Its abdomen was very much distended; this distension 
had appeared before death. Superficial inguinal glands somewhat enlarged and 
congested. Peritonitis indicated by some reddish serum and by strings of fibrine 
stretched across coils of large intestine. The latter were greatly distended with gas 
and semi-liquid feces. Glands of meso-colon hemorrhagic. Lungs collapsed, quite 
red, HExostoses as large as marbles on four right lower ribs near cartilages. No 
other lesions observable. This animal, therefore, had not contracted the disease as 
observed in those animals with which it had been penned. 
Another animal (No. 378) which had been growing poor for nearly a month and 
finally died was also affected with extensive hepatization of the lungs. The lesions 
observed were briefly as follows: 
Scaly patches on the side of neck, on buttocks. About 25° of yellow serum in 
abdomen, a few strings of coagulated lymph on coils of intestines. Liver dark, re- 
sistant. Gall bladder distended with dark brownish bile. Stomach empty, bile- 
stained. Mucosa of intestinal tract dark, probably due to venous stasis ; no ulcera- 
tion. Heart large, flabby. Right heart filled with a very dark soft clot. Left 
auricle distended by a very firm white thrombus, left ventricle partly filled by a 
dark clot. All vessels leading to and from heart filled with moulds of dark coagu- 
lated blood. Lungs partly collapsed. Slight fibrous adhesion of each lung to chest 
_wall. The cephalic and ventral lobes of each lung and the azygos lobe airless, solid, 
of a grayish-red, semi-translucent, or waxy appearance ; bronchi plugged with a 
glairy mucus. At least one-half of the left principal lobe and one-third of the right 
hepatized, being the ventral portions. The disease was moving from the ventral to 
the dorsal side, 7. e., from below up when the animal is standing, the only portions 
not affected being those nearest the back-bone. 
Although forms resembling swine plague bacteria were found®n microscopic ex- 
amination in the solidified portions, a rabbit inoculated on the ear did not succumb. 
The microscopic examination of sections made from that portion of the lungs 
most recently affected and stained according to Gram gave some interesting results. 
Capillaries very much distended, with red corpuscles, so that alveolar walls appear 
very thick. Alveoli and smallest air tubes plugged with dense masses of cells, 
epitheleoid andround. In the alveoli are found chains of cocci (streptococcus) from 
five to twenty in a chain, winding if and out through the cell mass. They are ap- 
proximately 1 micromillimeter long, slightly oval, and stain very deeply. In some 
groups of alveoli these streptococci are very numerous, in others they are few in 
number, or else replaced by another form consisting of minute bacilli in groups of 
few to many, usually within the protoplasm of the cells contained in the alveoli. 
These bacilli resemble tubercle bacilli very closely. In some alveoli they are ex- 
ceedingly numerous. These two forms of bacteria, stained dark biue and strongly 
contrasting with the brown color of the cells (bismarck brown), were perhaps the 
only ones present, none others in sufficient numbers to be detected. 
Cultures from blood of heart, spleen, and liver remained sterile. 
