SE sp MIS a aie Se SER Wi ad ei He eT ee ee ie eS 
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. 
BUREAU OF ANIMAL INDUSTRY. 505 
died next day. A gelatine and a liquid culture were both pure, containing only 
swine plague bacteria. At the same time the presence of these bacteria in the peri- 
cardial cavity of the pig was demonstrated by roll cultures. The presence of swine 
plague bacteria in both lungs and pericardium was thus amply proved. The latter 
was also invaded by other bacteria, a vibrio and a streptococcus being among the 
number. 
though microscopical examination failed to reveal any bacteria in the spleen of 
this animal the characteristic motile hog-cholera bacteria were obtained from it in 
both gelatine and liquid cultures. The colonies in the gelatine tube were very few 
in number. Two mice inoculated therefrom died rather prematurely in twenty- 
four and forty-eight hours, respectively, with the specific bacteria in the spleen. 
. 
Pig No. 366. 
lung tissue 
pericardial exudate 
rabbit (ear) June 30 3 mide spleen 
died July 2. died say 2,3 
(swine plague) (swine plague) mouse, June 30 
died July 2 
(swine plague) _ b.i.cult. gel. cult. 
(hog cholera) 
: » _b.i.cult. 
died Faw ‘g hog cholera 
(prematurely) 
Within several days of the death of this animal two pigs which had been placed 
in the same pen died of acute hog cholera, without any hepatization of the lungs. 
Pig No. 414 was placed in the infected pen June 21, for the purpose of keeping up 
the disease of hog cholera, which was apparently dying out. The animal died July 
6, after appearing dull for afew days. At the autopsy the lymphatic glands were 
found but slightly affected, spleen enlarged and very much congested. Lungs 
normal, excepting a few subpleural petechiz. Czecum and colon covered with a 
large number of ulcers, the mucosa of the latter intensely congested. Thesame 
was true of the greater curvature of stomach. Very few hog cholera bacteria in 
spleen. A pure culture was obtained therefrom. 
Pig No. 416, put into the infected pen with No. 414, showed signs of disease July 
4,and died on the same day. Skin of abdomen deeply reddened. Lymphatic 
glands with cortex hemorrhagic. Spleen very large and gorged with blood. 
Lungs and heart normal, with exception of a few subpleural ecchymoses. Numer- 
ous petechiz on surface and in parenchyma of kidneys. Light hemorrhage into 
pelvis. Numerous subperitoneal ecchymoses on the large and the small intestines. 
Besides a general congestion of the mucosa of the latter there are a few small re- 
cent ulcers in cecum and colon. Hog cholera bacteria quite numerous in cover- 
glass preparation from spleen. A pure culture obtained therefrom. 
These three cases show that in the same pen two animals may be in contact with 
a third which has very extensive lung disease and not take the disease. It is barely 
probable that the period of exposure to the living animal, about eight days, was 
too brief a time for the transmission of the disease, or else the time elapsing between 
the exposure to this disease and the death of the animals from acute hog cholera 
was too short to allow the lung disease to make its appearance. We know as yet 
too little of this disease to offer anything but opinions concerning its origin and 
communicability. 
The source of the lung disease in the first animal (No. 366) is likewise very 
puzzling, when we consider that a number of animals had died of hog cholera 
without any sign of lung disease. 
BRIEF SUMMARY OF THE FACTS OBTAINED FROM THIS EPIZOOTIC. 
In the fifteen animals which died there was extensive disease of 
the lungs, excepting in the first (No. 406), which was very likely a 
case of hog cholera. In most of these the pleura was also involved. 
In the earliest four cases, excluding the first (Nos. 403, 402, 405, 407), 
there were lesions of the large intestine, of the character of an exu- 
date, of a partly croupous, partly diphtheritic character. In the two 
