134 P. KIDD ON SPONTANEOUS MOVEMENT OF NUCLEOLI. 
were not lymphoid corpuscles, for they were very large, much 
like columnar epithelial cells, at the same time somewhat 
irregular in their outline. It should be mentioned that as 
the frog was suffering from inflammation of the mucous 
membrane of the mouth, these special cells, from their large 
size, irregular shape, and the absence of cilia were probably 
young epithelial cells. On observing one of these cells after 
a short time a process was developed from its nucleolus, 
which very soon after was seen to undergo a change not only 
in length but also in direction. In two or three cases the 
processes given off from a nucleolus possessed a knob-like 
projection at their free end, which seemed to vary in distinct- 
ness in the course of the observation. After a few days 
another examination of the epithelial cells from the mouth of 
the same frog was made under similar conditions, that is to 
say, the cells were examined between two cover-glasses in a 
drop of “humor aqueus,” ona Stricker’s warm stage. Again, 
amoeboid movements were observed in the nucleoli of these 
special cells, two or more processes were observed to spring 
from several nucleoli. In some cases these processes were 
provided with a small lateral branch, and in one instance 
such a branch disappeared and a corresponding branch 
appeared at another point. 
From Waldeyer’s Report in the ‘ Jahresbericht tiber die 
Leistungen und Fortschritte in der Anatomie und Physio- 
logie’ for 1873, I find that Auerbach in his treatise on 
nuclei attributes amceboid movement to the nucleoli from 
certain irregularities in their shape; he has not, however, 
observed these movements. Metschnikoff, on the other hand, 
has observed movement in the nucleoli of salivary glands of 
larva of ants. Balbiani and v. La Valette St. George 
observed the same in the germinal spot (7. e., nucleolus) of 
the ovum of the spider and dragon-fly. Quite recently Dr. 
Alexander Brandt described amceboid movements observed 
in the nucleoli of the ova of Blatta Orientalis (Max Schultze’s 
Archiy, vol. 10, part iv). 
