NOTES AND MEMORANDA. 175 
narcotized, and then the solid nitrate of silver is rubbed over 
the entire surface of the cornea. When this is done in the 
living state all the layers become stained in a few minutes. 
The cornea is now cut out and placed in a weak solution of 
acetic acid and water for twenty-four hours. By this time it 
has swollen up and can be easily split into layers. When 
one of these layers is placed in glycerine and examined with 
a low power (No. 2 Verick), a cloudy zone is noticed sur- 
rounding the cauterized spot, while outside this the cornea 
appears to be normal. The inflammatory process does not 
affect the whole cornea, but is most marked at a short distance 
from the point of greatest irritation. And, now, if we 
examine this cloudy area with a higher magnifying power 
(No. 7 Verick, or No. 10 Immersion Hartnack), we can dis- 
tinguish certain well-marked changes in the corneal tissue, 
and are thereby enabled to interpret their history. The first 
noticeable phenomenon, and probably the earliest change 
that occurs, is a remarkable contraction of the processes of 
the corneal cells, so that instead of fine processes uniting the 
cornea-cells together we see a dense network with very little 
intercellular substance. In certain parts the contraction has 
gone so far that the cornea-cells are individually isolated. 
What next occurs, and is so clearly demonstrated as not to 
leave the slightest doubt on the subject, is fissiparous division 
of this dense network of cornea-cells and their contracted 
processes. The divided parts are at first irregular in shape, 
but when separated from the parent stem, as afterwards 
happens, become rounded, a nucleus is developed in their 
interior, and they become individual pus-corpuscles. In 
some places the divisions are extremely small, and, in these 
instances, it is probable that pus-corpuscles are not im- 
mediately formed; but that they remain as the granular 
material of fully formed purulent fluid. The intercellular 
substance next becomes disintegrated, and we have a 
microscopic abscess as the result. He has never found any 
evidence to show that the large numbers of pus-corpuscles 
seen in this point of suppuration emigrate from the vessels 
surrounding the border of the cornea, and is of opinion that 
the changes met with in the layers of the inflamed cornea 
are a prototype of what occurs in other tissues. 
Professor Max Schultze—A recent number of the ‘Archiv 
fir Mikroskopische Anatomie’ contains a memoir of this 
lamented anatomist, from which we take most ot the fol- 
lowing account. Max J. S. Schultze was born in 1825, at 
Freiburg, in Breisgau, and was the son of C. A, S. Schultze, 
at that time Professor of Anatomy and Physiology there,though 
