QUARTERLY CHRONICLE OF MICROSCOPICAL 
SCIENCE. 
HISTOLOGY: 
II. TheCell.—1. Spontaneous Movements of the Nucleolus.— 
Brandt (‘Arch. f. Mikr. Anat.,’ Vol. X., p. 505) remarks that 
in the modern cell theory the function and nature of the 
nucleus have become obscure and little regarded. He 
himself describes some observations on the nucleolus (ger- 
minal spot) of an ovum from the ovary of Blatta orientalis. 
The ovarial eggs of this insect are cells with a granular 
protoplasma and a large transparent nucleus containing a 
nucleolus. The latter varies both in size, shape, and posi- 
tion in the nucleus, when different cells are compared. 
Continuous observation shows that these differerences depend 
upon amceboid movements of the nucleolus effecting both 
alteration of shape and locomotion. The movements 
are slow, but stimulated by heat. Bodies sometimes seen 
within the nucleus which are rather to be regarded as pre- 
cipitates, and show no movements. These may be dis- 
tinguished as pseudonuclei. 
2. Experimental Production of Giant-Cells from Colourless 
Blood-Corpuscles.—Ernest Ziegler (‘ Centralblatt,’ nos. 51 
and 58, 1874), cut from murror-glass plates of different 
sizes, some square and some oblong, ground off the edges 
carefully, and affixed to each with porcelain cement a fine 
cover-glass of the same size, so that there remained between 
the glass lamellae an empty capillary space, accessible from 
all sides, with the exception of the corners. These plates 
were brought under the skin and periosteum of dogs and 
rabbits, or were introduced into one or other of the large 
cavities of the body. This was done under the impression 
that the colourless blood-corpuscles would penetrate into all 
the spaces, would wander under the cover-glass, and there, 
independently of the organism, be nourished by lymphatic 
1 The articles in this division are arranged under the following heads :— 
J. Text-books and Technical Methods. II. The Cell in General. III. Blood. 
IV. Epithelium. V. The Connective Tissues. VI. Muscle. VII. Nervous 
System. VIII. Organs of Sense. IX. Vascular System. X. Digestive 
and Respiratory Organs and Glands. XI. Skin and Hair. XII. Urinary 
and Sexual Apparatus. 
The Editors will be glad to receive, for the purpose of making this 
record more complete, copies of separate memoirs or reprints from pe- 
riodicals, which must otherwise often escape notice. 
