378 JEREMIAH M‘CARTHY., 
in clusters and sometimes in spindle-shaped groups, the long 
axis of which corresponds to the long axis of the ganglion. 
Occasionally a solitary ganglion-cell may be seen, but this 
does not appear to be interposed in the course of a nerve- 
fibre, as some writers describe, but rather to result from the 
section having passed through a terminal cell of one of these 
spindle-shaped groups. ach cell is bounded by a very 
sharply defined border, in which nuclei of connective-tissue 
corpuscles may be distinguished. Within this is a broad 
band of apparently hyaline substance with nuclei imbedded 
in it. This hyaline layer is broadest where a nucleus is 
situated, in parts where there are no nuclei becoming about 
one third narrower. Examined with a No. 11 immersion 
Hartnack, it appears faintly fibrillated. The nuclei are 
mostly round, but some are oval, and in each of thema 
nucleolus and some granules may be seen. With hema- 
toxylin they assume a pale violet colour, thus presenting a 
marked contrast to the nuclei of the outermost layer of the 
capsule, which take a much deeper tint. The number and 
arrangement of these nuclei are variable. In some capsules 
there are only three or four such nuclei, in others of equal 
size, eighteen or twenty. Again, they are sometimes isolated, 
sometimes in pairs, either overlapping or barely separate, and 
sometimes in groups of seven or eight; this last arrangement 
being most frequently seen at the junction of a nerve with 
a ganglion-cell, where the section admits of such continuity 
being traced. This hyaline layer, in most cells, has no defi- 
nite limit internally, but shades off into a cloudy substance, 
which in turn is continuous with a molecular mass, in which 
is imbedded a very large nucleus. This molecular mass is 
not the same throughout. Internally it often appears faintly 
fibrillated, concentrically with regard to the nucleus, while 
externally it has a more granular appearance, these granules 
also being concentrically arranged, and is of a darker colour. 
This outer part very usually contains a large irregular group 
of pigment-granules. The nucleus has a very definite mem- 
brane, and is composed of some very finely granular matter 
with a few larger granules and a nucleolus. On careful ex- 
amination some differences may be detected in the nuclei of 
different cells. In some of the smallest ganglion cells the 
nuclei have a more compact appearance, and stain of a pale 
violet colour, so as, but for their larger size and sharply 
defined borders, to very much resemble the nuclei of the 
hyaline layer. In some of the larger cells the nuclei, on the 
contrary, have an almost vesicular appearance, are quite 
colourless, and the nucleoli are unstained, shrivelled, and 
