MEMOIRS. 



Observations on the Structure of Cells and Nuclei. By 

 E. Klein, M.D., F.R.S. (With Plate VII.) 



II. 



C. Epithelial and Gland-cells of Mammals. 



In the first part of this paper^ I have shown that the proto- 

 plasm of the epithelial cells of the stomach of the newt consists of — 

 {a) an iniraceUular nehvork of minute Hbrils, and (c) an interfihril- 

 lar hyaline substance, contained in the meshes of the former. The 

 interfihrillar substance, while changing into hygroscopic mucin, 

 increases considerably in bulk — whereby also the meshes of the 

 intracellular network become enlarged — and thus produces the 

 transformation of the ordinary columnar epithelial cell into a 

 '^ goblet-cell." 1 have further shown that the nucleus of these 

 cells (like those of Salamandra maculata, demonstrated by Prof. 

 Elemming) contains within its membrane a network of minute 

 fibrils, which I designated as intranuclear nettoorh, and that this 

 is in direct connection with the intracellular network. 



Extending these observations on epithelial cells of mucous 

 membranes and glands of mammalian animals, I am able, not 

 only to confirm the principal points as regards the structure of 

 the cell-substance and nucleus of epithelial cells of stomach of 

 newt, but I am in a position to add to these other new facts, 

 which seem to me of interest in morphological as well as physi- 

 ological respects. 



The objects which I examined are the following : 



1. The epithelial cells of the mucous membrane of the intes- 

 tine, including the cells lining the crypts of Lieberkiihn. 



2. The ciliated epithelial cells lining the tubes of the epididymis. 



3. The gland cells of the submaxillary gland of dog and man. 



4. The gland cells of mucous glands. 



5. The epithelial cells of the glands of stomach and of 

 Brunner's glands. 



6. The gland cells of liver. 



7. The cells of laminated pavement epithelium, including 

 those of the rete Malpighii of the epidermis. 



1 This Journal, vol. xviii (New Ser.), July, 1878, p. 315. 



VOL. XIX. NEW SER. I 



