160 DR. E. KLEIN. 



narrow body and small lumen of the peptic glands of the fundus 

 of doge's stomach form a very marked contrast with the broad 

 tubes and large lumen of the so-called mucous glands of th e 

 pylorus of the same animal, and for this reason the above-named 

 change of the tubes in these characters is of importance. 



(e) In this I do not refer, like Ebstein (1. c), to the 

 occurrence of "a few peptic gland tubes amongst a series of 

 mucous glands/^ but to afeio broad tuies loltli large lumen lined 

 with columnar epithelium and containing only a few jjarietal cells, 

 amongst a majority of ordinary peptic gland tubes. These broad 

 tubes resemble the tubes of the pyloric glands in every respect ; 

 they are branched, and their columnar epithelium lining the 

 broad lumen in no way differs from that of the above glands ; 

 and if it were not for the facts (a) that we still find a few parietal 

 cells, and {b) that towards the neck they pass into a narrow 

 gland tube with small lumen and a goodly number of parietal 

 cells, we could not distinguish them from the tubes of the mucous 

 glands. 



The preparations to which I here refer were hardened in the mixture of 

 chromic acid and spirit mentioned several times ; the lumen of the peptic 

 gland is lined with cells ichich in all respects resemble those lining the 

 tubes of the pyloric glands, i. e. transparent columnar cells with the charac- 

 teristic cup-shaped, i. e. compressed nucleus close to the membrana propria. 

 In this I see a fact in support of Ebstein's theory of the identity of the 

 chief cells of the peptic glands with the cells lining the pyloric glands. 



I have before me a specimen in which I find the following con- 

 dition : a very large duct — 0*08 mm. broad and 0'28 mm. long — 

 branches into,/o?^r tubes,two of them differ in no way from the other 

 peptic glands present in the vicinity ; they are relatively narrow, 

 have a small lumen, are somewhat convoluted, and present the 

 usual number of parietal cells. The other two are exactly like 

 them in the neck and the beginning of the body of the tube, 

 but in the deeper part they differ inasmuch as both are very much 

 broader ; one of them (No. 3) is just as broad and its lumen just 

 as large as a gland tube of the pylorus ; and the other (No. 4) is 

 somewhere between the ordinary peptic and pyloric gland. And 

 in conformity with this alteration we find also in No. 3 very feio 

 parietal cells — I count two parietal cells only from the neck to 

 the fundus of the tube. In No. 4 they are more numerous, but 

 considerably fewer than in Nos. 1 and 3. 



The breadth of tube No. 1 or 2 does nowhere exceed 0013 mm., its 

 lumen is hardly measurable with an Ob. 7 of Hartnack ; in tube No. 3 the 

 breadth of the tube is 007 mm., and the lumen 0*013, i. e. the lumen alone 

 is as big in No. 3 as the whole tube in Nos. 1 and 2. 



After these facts I am justified in saying that the two kinds 

 of glands, viz. the peptic glands of fundus and the so-called 



