404 GLANDULAR EPITHELIUM AND DIVISION OF NUCLEI. 



These bacteria could not have been the cause of deaths nor, most 

 assuredly, could they have derived their origin from the liquor 

 ammonia which had been resorted to to excite the inflammatory 

 process. 



It would seem from these results that the living tissue elements 

 of the body itself play a much more important part in the 

 elaboration of septinous and allied poisons, than what has been 

 of late ordinarily ascribed to them. 



Such^ so far as I have been able to learn, are the main facts 

 which have been recorded with regard to the microphytes of the 

 blood in health and in diseased conditions. 



Calcutta; 



Auffiist, 1878. 



Observations on the Glandular Epithelium and 

 Division of Nuclei in the Skin of Newt. By 

 E. Klein, M.D., F.R.S. (With Plate XVIII.) 



In number 17 of the ' Centralblatt f. nied. Wiss./ 1879, I 

 have described giant nuclei of the huge epithelial cells lining 

 the large saccular glands of the skin — tail — of newt ( Triton 

 cristatus). I have shown that these nuclei, when examined 

 fresh in aqueous humor of frog, show an exceedingly distinct 

 network of more or less uniform fibrils and trabecular ; 

 owing to the large size of the nuclei their network can be 

 seen in all its details even under a low power. Many of 

 these giant nuclei show in the network of the highly 

 refractive fibres and trabecule cylindrical or irregular 

 accumulations corresponding to nucleoli, others are free of 

 them. I have also shown that both the nucleoli, when they 

 exist, and the fibrils and trabeculse, possess vacuoles ; and 

 further, that on the warm stage the intranuclear network 

 shows contraction, Avhereby the outline of the nucleus 

 changes in a similar manner as in cells while undergoing 

 amoeboid movement. 



Of the gland cells themselves I have mentioned that they 

 likewise show amoeboid movement, in the course of which 

 larger or smaller knobs are pushed out, which become with- 

 drawn or constricted off altogether, and then move inde- 

 pendently. These cells are also in other respects remarkable, 

 viz. that they are capable of ejecting their nucleus (the 

 above giant nucleus), and after this continuing their move- 

 ment. Some of them are filled with discoid or spherical fat 

 molecules of various sizes, and they are capable of ejecting 



