414 DR. B. KLEIN. 



hence many of the fibrils are seen endwise as bright dots or 

 " granules." This appearance is incorrectly interpreted 

 by Mayzel; Eberth, and especially Schleicher and Pereme- 

 schko, who describe the nuclei as at first containing 

 ''granules/^ which gradually arrange themselves into fibrils. 

 I am at one with Flemming in opposing such an interpre- 

 tation, since I maintain, with him, that before the fibrils 

 arrange themselves into "convolution^' and '^basket," there 

 is already a well-formed reticulum in the nucleus. 



Nuclei of this kind can be seen in the deepest and in the 

 next following layer. 



Then we find nuclei somewhat larger, but without any 

 limiting membrane whatever ; they may be described with 

 Flemming as containing deeply-stained filaments arranged 

 in the shape of a "rosette " or "wreath;" the filan rntsare 

 in difierent examples of difierent thickness; they form a 

 loop at the periphery, and approach each other in the centre 

 (see figs. 14, 17 and 18). Between the nuclei with "con- 

 volutions" or " basket "-shaped arrangement of filaments, 

 and those in which the latter form a " rosette " or " wreath," 

 we find many intermediary forms. See also Flemming, 1, c, 

 p. 376, and the beautiful figures on Plate XVII, accompany- 

 ing his paper. 



Further, we pass from these to large nuclei, also without 

 any membrane, in which the deeply-stained fibrils are 

 arranged like a single aster ("Monaster"), apparently termi- 

 nating freely at the periphery, but connected into a central 

 network. Mr. Balfour has also described and figured this 

 form as the " stellate variety " of dividing nuclei of the 

 developing ova of the embryo (this Journal, No. Ixxii, p. 

 395). Like Flemming, I also find the fibrils of this form, 

 as a rule, much thicker than in any of the preceding ones 

 (see fig. 19). 



Next, we trace these into nuclei without a membrane, in 

 which the fibrils are similar in appearance to the preceding 

 ones, but arranged as a double aster " (Dyaster) " (see figs. 

 20,21,22). 



The majority of the forms described as '^ rosette ^' or 

 " wreath," and as " monaster " and " dyaster," are found 

 amongst the deepest layer, but occasionally we meet one or 

 the other of them in the next following, or even the 

 further layer ; they are all very conspicuous on account of 

 their size, and owing to this the cell itself is very much 

 bulged out laterally. 



In the " dyaster," that I find in my specimens, the fibrils 

 of one aster are connected with those of the other. The 



