162 DR. E. KLEIN. 



N. lingualis) connected with the gland there is a large lymphatic 

 vessel running parallel with the nerve ; this lymphatic contains 

 in its interior a venous blood-vessel. Fig. 10 shows this vessel 

 and the vein in transverse section. The wall of the lymphatic 

 consists of the lining endothelium, outside this of a delicate 

 intima and circular muscular media, and further^, of a reticu- 

 lated connective-tissue adventitia. The outer surface of the 

 vein, i.e. the one facing the lumen of the lymphatic, is covered 

 with a layer of endothelium. 



Eollowing the connective tissue accompanying the ducts and 

 large blood-vessels into the lobules, the lymphatic tubes become 

 of course scarcer, and more reduced in the area of their distri- 

 bution. At the same time they lose the character of tubes and 

 assume more of the nature of lymph-spaces and clefts between 

 the connective-tissue trabeculse and the fascicle plates. 



The septa between the lobules, belonging to the same group 

 or lobe contain as a rule lymphatics of the same nature as just 

 mentioned, that is to say, they appear more of the nature of 

 lymph-clefts and spaces in the connective tissue such as is men- 

 tioned by Gianuzzi and Heidenhain. Sections through the 

 parotid and submaxillary of the dog, such as represented in figs. 

 13 and 14, whose lymphatics had been injected, show the dis- 

 tribution of these vessels and spaces very well. 



In the submaxillary of the dog and rabbit, and in the sublin- 

 gual of the guinea-pig and rabbit, i.e. in those glands that 

 contain conspicuous ganglia (see below), we notice that some 

 of the ganglia and the afferent and efferent nerve branches 

 are surrounded or accompanied respectively by a lymphatic 

 vessel. 



In the glands that contain a considerable amount of the inter- 

 lobular connective tissue, such as the parotid of the dog and 

 ape, the submaxillary gland of man, ape and dog, the lymphatic 

 vessels around the ducts and around the blood-vessels bear the 

 same intimate relation, i.e. that of an open communication, to 

 the spaces existing between the fascicle plates and between the 

 bundles connecting neighbouring plates as described above. 

 This relation has been very minutely described and figured in 

 my former Eeport (for 1879), and I need not therefore again 

 enter into this subject. 



The circumalveolar lymph-spaces which, as mentioned above, 

 were first demonstrated by Gianuzzi, form one intercommunicat- 

 ing system. They anastomose with the lymphatics hitherto men- 

 tioned in two ways : — (1) Af the margin of the lobules they open 

 into the lymphatic vessels, or in the absence of these, into the 

 lymphatic clefts situated in the connective tissue between the 

 lobules; (2) those (/ ^^le more central imrts of the lobule empty 



