DR. BEALE, ON NERVE-FIBRES AND CELLS. 99 
Beale’s views would not be tenable. But, Dr. Beale states, 
that after very numerous observations upon the ganglia of 
man and animals, especially those of the frogs, he is com- 
pelled to conclude ‘that neither apolar nor unipolar cells exist 
anywhere, and that nerves never terminate in free ends in any 
tissues. 
All nerve or ganglion-cells are bipolar or multipolar. The 
existence of cells with only one fibre is very doubtful, even in 
the case of very young cells, for what seems to be only a single 
fibre under a power of 250 or 300 diameters, is found to be 
composed of two or more fibres when the highest powers are 
used. Dr. Beale, in many cases in which, at the first ap- 
pearance, the ganglion-cells seemed to be without any fibre 
whatever, has been able to show several springing from 
different parts of them. He has also demonstrated that the 
so-called Remak’s fibres are true nerve-fibres ; and in affirm- 
ing this he differs from most observers in the present day ; 
for it is generally held that this kind of fibre is nothing else 
than a modified form of connective tissue, an extension of 
which is supposed to form the capsule of the ganglion-cell. 
These fibres, as is shown in his specimens, contain a great 
number of nuclei, and are continuous with the outer part of 
the germinal matter of the ganglhion-cell. 
With regard to the termination of the nerves im voluntary 
muscles, and especially in those of the mouse, Dr. Beale has 
given the results of his investigations in a very valuable paper 
read before the Royal Society in June, 1860. The conclu- 
sions which he arrived at are as follows : 
Ist. That every elementary fibre of the striped musle of the 
mouse is more or less abundantly supplied with nerves. 
2nd. That the nerves terminate in a network outside the 
sarcolemma. 
3rd. That the nerve-fibres which form this network are 
pale fibres abundantly nucleated. They cross the muscular 
fibre at short intervals in every part, and often at right angles. 
Ath. That these pale fibre are directly continuous with the 
dark-bordered fibres. 
Since the publication of Dr. Beale’s paper, Kihne and 
Kolliker have studied the subject, and the conclusions which 
they have arrived at are quite inconsistent with those of - 
Dr. Beale. 
Kuhne states that he has observed the thin breast muscle 
of the frog, and found that the pale nerve-fibre, at one point, 
penetrates the muscular fibre, and divides beneath the sarco- 
lemma into two or more fine fibres, which terminate in peculiar 
oval bodies, considered by him as a orgaus. He further 
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