470 J. R. BRADFOJID AND H. G. PLIMMER. 



Fig. 22 (Oc. 12). — From same specimen, sliowiiij^ conjugation completed, 

 in which the two micronuclei are fused into one large dot. 



Fig. 23 (Oc. 12). — From blood of rat, eighth day, siiowing an unusual form 

 of conjugation in whicli the central micronuclei seem to have disappeared, 

 whilst two others are being detached from the macronuclei. 



In all these figures, from 18 to 23, the macronucleus seems to be in a state 

 of activity, as shown by its alteration in shape, the chromatin being principally 

 arranged peripherally. 



Figs. 24 — 27 (Oc. 18). — Amceboid forms from the bone marrow of a spleen- 

 less dog, twenty-one days. The flagella are not visible in any of these, but 

 probably were broken off in the process of preparation. In Figs. 25 and 27 

 division is taking place, and the macronuclei in all appear to be in a state of 

 activity. In Fig. 26 the organism is lengthening out, as if it were becoming 

 an ordinary adult form. 



Figs. 28 — 31 (Oc. 18). — From the bone marrow of a spleenless cat, show- 

 ing amoeboid forms. In these the flagella are visible, and all the organisms are 

 undergoing division. In Fig. 31 there appears to be a complicated process of 

 division, the smaller organism at the upper part appearing to have four micro- 

 nuclei and two macronuclei, as if preparing for some such form as is shown in 

 Fig. 31 «. 



Fig. 31 a (Oc. IS). — From blood of a spleenless dog, eighth day, showing 

 four adult organisms being given off from an amoeboid mass. 



Figs. 32, 33 (Oc. 18). — From bone marrow of a spleenless dog, showing in 

 Fig. 32 a simple amoeboid form, and in Fig. 33 one in which the micronucleus 

 is divided. 



Fig. 34 (Oc. 18). — From blood from lung of mouse, seventh day, showing a 

 flagellated amceboid form full of granules, similar in colour to those seen in 

 certain adult organisms, as shown in Figs. 6 — 8, 



Fig. 35 (Oc. 18). — From same specimen, showing a dividing flagellated 

 amoeboid form. 



Fig. 36 (Oc. 18). — From the same specimen, showing an amoeboid form 

 lengthening out, as if becoming an ordinary adult form. 



Fig. 37 (Oc. 18). — From blood from lung of rat, ninth day, showing a 

 plasmodial mass in the centre with micro- and macro-nuclei scattered about in 

 a mass of protoplasm, and at the outside a few amoeboid forms being detached. 



Fig. 38 (Oc. 12), — Smear from spleen of rat, eight days, showing the Plas- 

 modium, with its numbers of micro- and macro-nuclei wedged in between the 

 splenic cells. A few red corpuscles are also drawn. 



Fig. 39 (Oc. 12). — From a scraping from the lung of a mouse, seventh day, 

 showing a plasmodial mass with cells from the lungs which are accidentally 

 present as the result of the method of preparation. 



