6 Bulletin No. 159 



sects among them. The situation is an excellent one for 

 Simulium, but the weather was threatening- and dark and 

 with the limited time at my disposal I was compelled to 

 give up the search without finding larvae, though I secured 

 a number of other insects from among the rocks. I am 

 confident that Simulium larvae can be found here in the 

 spring of the year. 



At Pineville I searched the rapids of Cumberland River 

 with care, and explored Clear Creek between the Pine and 

 Log Mountains, giving special attention to the creek because 

 a case of pellagra, in charge of Doctor Foley, of Pineville, 

 was located on its banks. The dwelling in which this 

 patient lives is on the banks of the creek in much the same 

 position relative to the water as the one on Laurel River at 

 Corbin, yet from what I learned by conversation with the 

 patient it was probable that she had contracted the ailment 

 at another place, though similarly situated with reference 

 to the stream. The stream was inspected at intervals above 

 this dwelling and below it down to its junction with the 

 Cumberland. Numerous insects were found in it, and sit- 

 uations exactly suited to the breeding of Simulium, yet 

 none were found. 



In the Cumberland River as it flows through the Gap of 

 the Pine Mountains I spent some hours on two days and 

 found a few Simulium larvae in its rapids among a scant 

 growth of Nitella, with many other insects characteristic of 

 swift-flowing, rocky streams. 



At Cary, three miles north of Pineville, is a mining camp 

 on the left Fork of Straight Creek. In company with Doctor 

 J. H. Hendren of Cary I visited here some of the most 

 interesting cases seen on my trip. At the outskirts of the 

 settlement, perhaps one hundred and fifty feet from the 

 stream, is a dwelling in which were four cases of pellagra, 

 which, judging from Dr. Hendren's statements, had origin- 

 ated at this place. The stream was shallow at the time of 

 my first visit ( September 1 ) and consisted of stretches of 

 quiet water a few feet in depth, in which some fishing with 

 hook and line was going on, alternating with rocky rapids 



