276 Observations upon the 
jured parts examined. The bone overwrap- 
ped considerably, the faces of the fracture 
were sharp and irregular, the surrounding 
muscles much lacerated, anda considerable 
quantity of blood effused into the cellular 
membrane. 
This observation describes a state of the in- 
Jury previous to. the commencement of any 
action of reparation, and stands as the point 
from whence to commence our observations. 
The swelling found at this period, arises from 
extravasation of blood, and is essentially dif- 
ferent from a succeeding tumefaction, the 
consequence of increased action of the blood- 
vessels, and previous to. which this bloody ex- 
travasation is considerably diminislied by the 
action of the absorbent vessels of the. part. 
The asperities of the fractured faces are to 
be carefully noted, since they are the chief 
cause of the laceration of the muscles, con- 
stantly present in a greater or less degree, 
and possessing a. considerable influence over the 
termination of the case. In all the succeed- 
ing experiments; overwrapping of the bone 
was constantly found, and in the fracture of 
long bones it is rarely absent unless prevented 
by sotie mechanical cause... Betwixt the in- 
fliction of an injury, and the commencement 
of a curative process, a certain portion of 
