ON THE ANTAGONISM BETWEEN TWO 

 DIFFERENT SALTS IN THE ENZYMATIC ACTIONS. 



Tetsutako Tadokoko, Nögakiishi. 



ffl /ifr i^ ± fiP 



To these days, some different experimental results for the influences of dif- 

 ferent neutral salts upon the enzymatic actions have been reported by many authors. 

 Many contrary points, however, are found among those which are written in the 

 Oppenheimek's "Fermente und ihre Wirkungen". These authors have reported 

 always the influences of one salt alone and there are no experimental data upon 

 the mutual and antagonistic actions between two different salts. 



Bang'^ reported that when the human saliva was mixed with secondary phos- 

 phate, the diastase of saliva lost its action but if this fluid was mixed farther with 

 common salt, the diastase recovered its action. Tiiereupon he exi)lained these 

 phenomena by introducing the fact that the compound of phosphoric-acid-jityalin 

 has no diastatic action while the compound of conimon-salt-ptyalin has. 



Recently, Michaelts and Pechstein'-' investigated the action of the diastase 

 of saliva in the mixture of salts, and their reports are as follows. "The saliva- 

 diastase acts better in N/500 NaCl-solution than in N/50 Na^ SO^^ -(- N/500 NaCl- 

 solution, and it acts better in N/50 NaBr + N/5000 NaCl-solution than in N/5000 

 NaCl-solution alone. It acts better in N/50 NaCl-solution than in N/50 NaBr-f- 

 N/50 NaCl-solution, and better also than in N/50 NaBr-solution, because here 

 N/50 NaBr-solution, because here N/50 NaCl-solution acts better than N/50 Nal^r- 

 solution." 



Thus until today, we can not find any report on the discussion of the antago- 



1) Bang, E. — Bibchem. Zeits., 32.417(1911). 



2) Michaelis, L. and Pechstein, H. — Biochem , Zeits., 59, 77—99 ("1914)- 



[Trans, of Sapporo Natural History Soc. Vol. VI. Part 3. Jan. 1917.] 



