68 öt^—- 1 ® ,a OMSM^ I- Sfc-C 



in weak alcohol suffer tlioroiigh damages in their microscopic structure : they are 

 quite valueless for histological works. And the present investigation is connected 

 a great deal with the histological studies. In addition to this, I could not obtain 

 a healthy turkey, the viscera of which may, if necessary, be compared with those 

 of the diseased one, in verifying the pathological changes suffered by the animal. 

 In my hope, therefore, to renew my work with the fresh material probably ob- 

 tainable in the coming summer, I left the present work in an imperfect state. 



The disease in question appears in early summer and grows severer towards 

 midsununer when it is most severe. Quite young chicken turkeys often show 

 symptoms of the disease, so that we may conclude that the infection goes on already 

 in the chicken. 



Tiie birds attacked by the disease soon become inactive, their plumage is turned 

 into a dirty colour, and sowe feathers become ruffled. At the same time, the belly 

 swells up enormously, and diarrhea soon follows, causing immediate death, Tliere 

 is little room in doubting that the direct mortal cause is diarrhea anil decreased 

 absorption of nutriment. In the following lines, I will point out some probable 

 causes of the diarrhea and decreased absorption, together with some other factors 

 standing in connection with these pathological phenomena. 



I wish here to express my warmest thanks to Prof S. HASHIMOTO and to 

 Prof Dr. S. HaTTA and Dr. T. XaTO for their courtesy shown by them during 

 the course of my present work. 



Part I. DESCRIPTIVE. 



It should fii'st be mentioned that the coeca as well as the liver undeigo, as 

 close examinations of the viscera of the preserved specimens show, manifest ])atho- 

 logical alterations. For the sake of convenience, the coeca and liver will be dealt 

 with separately. 



A. The CoBca. 



The coeca affected by the disease in question show a certain thickening, and 

 on the inner surface of their walls are detected curious elevations. The thicken] nu»- 

 varies in degree according to cases met with : it is, in some cases, confined to the 

 distal or to the proximal part, or to both the parts ; in other cases, it f )rms patches 

 circumscribing the walls ; in still other cases, the whole extent of the tube's wall is 

 uniformly swollen up. Wherever the coecal walls are thickened, the serosa is always 



