76 G. H. MONRAD-KROHN. M.-N. Kl. 



Yet it cannot be emphasized enough that one must not put too much 

 confidence in one single symptom or sign — modern medicine does not 

 believe in the old pathognomonic signs, and rightly so. It is only the 

 combination of the different symptoms and signs to a certain clinical picture 

 that can be called pathognomonic. All the same, when one speaks of 

 characteristic features of an illness, I think that the most characteristic findings 

 in leprosy are the peculiar facial paralysis and the concentric atrophy of 

 the small bones of hands and feet. They are the nearest approach to what 

 w^e to-day are allowed to call pathognomonic signs. 



