1923. No. 23. A CASE OF CONGENITAL MIOSIS. 23 



upon the dilatator. The resemblance between this tig. 19 and fig. 17 in 

 niv previous paper is clear. With regard to the "long connecting fibres" 

 I can also refer the reader to my previous paper (PI. \'III, fig. 18 and 19). In 

 the brother's eyes, too, they are built up of cells with an extraordinarily well- 

 marked rod-shaped nucleus, and I can therefore direct attention to tig. 19 

 in my previous paper as far as they are concerned. I have nothing special 

 to remark about the "short connecting fibres", except that in the brother's 

 eyes the elements in them have a shorter nucleus than those in the "long" 

 connecting fibres, and that thus, with regard to both brother and sister, I 

 have found on this point the reverse of what Forsmark found. 



As regards the nature of the stroma I think several of my photographs 

 give good inîormation. As a whole it appears to consist of a particularly 

 loose connective tissue. In places it has in a marked degree an appearance 

 resembling that of mucoid tissue. This is especially clear in figs. 8 and 9, 

 and is further shown in some of the other microphotographs. 



In certain places, however, the connecti\e tissue changes its appearance. 

 It is usually more rigid, for instance, and contains more cells behind the 

 sphincter. But in the \icinity of the "projections" it has also a greater 

 abundance of cells and is more deeply stained with eosin, in particular 

 becoming a bright red colour and assuming a certain hyaline, sclerotic 

 appearance behind the large muscle-plates that I have described as appearing 

 in connection with the "hooks". In fig. 17 we see, for instance, that the 

 connective tissue lying between the muscle-plate in front and the epithelium 

 behind, has a certain hyaline character, which I can only explain as having 

 originated through the constant pressure that the muscle-plate must be 

 assumed to have exerted upon it. I am inclined to explain in the same 

 way the similar appearance of the connective tissue behind the "long" 

 connecting fibres; for here, too, with the dilatator not functioning, it must 

 be assumed that the sphincter has exerted a con.stant pressure upon the 

 connective tissue, through its long ofi'-shoots. I have never observed in- 

 flammatory phenomena. 



Although ni}- investigations of the eyes of these twins had rather 

 différent results, they agree in so far as, in both, the whole of the periphery 

 of the iris is without dilatator muscle. As therefore that part of it which 

 exists has not had its normal attachment, it must be assumed that it has 

 not been able to function normally. The somewhat better degree of de- 

 velopment it had in the man's eyes his not therefore been able to make 

 the clinical discoveries in them dift'erent from those in the case of his sister. 



The drawings in figs, i and 2, and the letterpress-figures have been 

 executed by Fröken S. Mürch, the draughtswoman of the University Ana- 

 tomical Institute. The microphotographs I took myself. 



