98 



were in a condition of nitrogen equilibrium through the inges- 

 tion of a uniform diet, was productive of the following findings : 



1. An increase in body weight, aggregating from one and 

 one-half to two povmds in five days. 



2. An increased excretion of urinary nitrogen, the excess 

 nitrogen being mainly in the form or urea, ammonia and crea- 

 tine. 



3. A decreased excretion of creatinine and the coincident 

 appearance of creatine in the urine. The decreased creatinine out- 

 put is believed to indicate that the copious water drinking has 

 stimulated protein catabolism. The appearance of creatine is 

 considered evidence that the water has caused a partial muscular 

 disintegration, resulting in the release of creatine, but not pro- 

 found enough to yield the total nitrogen content of the muscle. 

 The output of creatine is therefore out of all proportion to the 

 increase in the excretion of total nitrogen. 



4. An increased output of ammonia which is interpreted as 

 indicating an increased output of gastric juice. 



5. A decreased excretion of feces and of fecal nitrogen the 

 decrease in the excretion of fecal nitrogen being of sufficient 

 magnitude to secure a lowered excretion of both the bacterial 

 and the non-bacterial nitrogen. 



6. A lower creatinine coefficient. 



7. A more economical utilization of the protein constituents 

 of the diet. 



8. A decreased excretion of fecal extractive nitrogen. 



9. A strikingly lowered output of carbohydrate in the feces, 

 thus indicating a more economical utilization of the ingested 

 carlx)hydrate. 



10. The increased body weight ; the lessened output of feces 

 and fecal nitrogen ; the decrease in bacterial and extractive 

 nitrogen of the feces ; the more economical utilization of the 

 protein and the carbohydrate constituents of the diet, all con- 

 tinued throughout the final period on a plan similar to that 

 established during the water period, instead of returning to the 

 conditions in force during the preliminary period. These facts 

 indicate that the influence of the water is not simply temporary. 



