254 E. A. MINOCHIN, 
is unfortunate from this point of view that these investigators 
have studied only pathogenic trypanosomes (T’. gambiense, 
brucii, and equinum), in which the kinetonucleus happens 
to be extremely minute and does not contrast sharply with 
a blepharoplast ; a peculiarity which may be characterised as 
a “ morphological curiosity.” If they had studied forms witha 
large kinetonuclens, like T’. grayi, I do not think they 
would have fallen into this error. Still more decisive against 
the view of Salvin-Moore and Breinl, it seems to me, is the 
eenus T'rypanoplasma (text-fig. B), in which n is as large 
as or even larger than N, and in which two distinct blepharo- 
plasts, from each of which a flagellum arises, can be made 
out plainly in good preparations; pace Salvin-Moore and _ 
Breinl], who would not concede, probably, that good prepara- 
tions can be made anywhere but in Liverpool. Finally, 
I am unable to agree that a structure of the same nature 
and reactions as the kinetonucleus exists in the interior 
of the trophonucleus. Here, again, a form such as 
T. grayiis very instructive ; the large kinetonucleus of this 
form stains very intensely and of a different tint from the 
eranules composing the nucleus. If a structure similar to 
the kinetonucleus were contained in the nucleus it would be 
impossible to overlook it. After what I have said above it is 
not necessary to point out that for Trypanoplasma the 
notion that the trophonucleus contains a body similar to the 
kinetonucleus becomes an absurdity. 
The difference, however, between the views of Salvin-Moore 
and Breinl and of myself is largely one of terminology, since 
the Liverpool investigators admit that the kinetonucleus 
arises from the nucleus. They describe it as originating by 
division of a karyosome, which they compare to the karyo- 
some described by Schaudinn, in Coccidium schubergi; 
a karyosome of this kind is a chromatic body, even if it con- 
tain a centrosome. Further, Salvin-Moore and Brein] regard 
the two nuclei (x and N) of a trypanosome as comparable to 
two differentiated gamete-nuclei, a comparison which I con- 
sider far-fetched and misleading in the highest degree, but 
