422 EXPORT OF THE COMMISSIONER OP AaRICULTUBE. 



PIG SUCCESSFULLY INOCULATED FEOM SHEEP AND LAHIB NO. 4. 

 (See supplementary report, page 101.) 



This experiment, referred to in the text of the last report, is now furnished 

 in extenso with the necropsy of the infected pig. It will be seen that 

 the pig was inoculated twice, at an interval of fifteen days, with the 

 mucus from the anus of the infected sheep, and one with scabs from the 

 ear of the lamb. Enlarged lymphatic glands were observable before 

 the last inoculation, and six days after it tliere was a febrile tempera- 

 ture, and the more violent manifestations of the complaint. 



After death the following characteristic lesions were observed: The in- 

 testines had patches of congestion, the follicles were enlarged and the 

 rectum ulcerated ; purple discolorations were present on the liver, kid- 

 neys, and heart; the lymphatic glands were enlarged and congested, of 

 a deep red, in some cases almost black. 



This evidence as to the nature of the disease was clear enough, but 

 to substantiate it the following experiment was undertaken : 



SUCCESSFUL INOCULATION FEOM THE PIG INFECTED BY THE SHEEP 



NO. 5. 



The pig designated as "^o. 5 in this rt^port was inoculated with scabs 

 from the ear and eyelids of pig No. 4, and though this caused little 

 change of temperature, it was followed by all the other prominent symp- 

 toms of the disease. On post-mortem examination on the twelfth day 

 after the inoculation, the characters of the plague were found weil 

 marked. The red and black blotches on the skin were extensive, the 

 ears blue, the intestines extensively congested with enlarged follicles in 

 the caecum and colon and blood extravasations and ulcers in the rec- 

 tum. Purple discolorations and petechias were numerous on the liver, 

 kidneys, and heart, and finally the lymphatic glands in general were in 

 part congested of a deep red, and in i)art pigmented as the result of a 

 previous congestion. 



Here, then, in the second generation of the poison from the sheep we 

 have the symptoms as well marked and the course of the disease as 

 rai^id and severe as in its first remove from the ovine subject. 



PIG SUCCESSFULLY INOCULATED FEOM THE INFECTED LAMB. 



In experiment No. 6 of the present report is given the record of a pig 

 inoculated from the swelling in the axilla (near the seat of inoculation) 

 of the lamb. The inoculation produced fever, with the general malaise, 

 moiDing, peevish grunt, inappetence, and cutaneous blotches of the 

 swine-plague. When killed, on the eleventh day, the skin presented 

 a number of red and purple blotches, and was covered with the black 

 unctuous exudation so frequent in this disease. The bowels contained 

 patches of congestion, the csecum and colon enlarged, and the follicles 

 and the rectum ulcerated. The liver, kidneys, lungs, and heart had pur- 

 ple blotches. Finally the lymphatic glands in the abdomen were en- 

 larged and congested of a deep red or black, and those in the chest and 

 guttural region darkly pigmented. This is as unequivocal a case as those 

 already recorded, and fully confirms our position that the virus of this 

 disease may be transmitted through the sheep and conveyed back to the 

 pig with active effect. 



