49 JLelter from Dr. Thornton on the Coiv-Pox, 



Hsiially in company with his father, for the carl of Lonsdalf ; 

 and going to Penrith on the fifth day after inoculation, he 

 drank a pint of strong-beer given him by one Pellet, at Mr, 

 Hutchinson's brewery, and came back that same day with 

 his team, having walked upwards of fifteen miles. In con- 

 sequence there was an attempt towards forming a kind of 

 eruption, one pitstnle appearing on the breast, and another 

 on the check, which actually saibOed over, and he passe;! a, 

 Testles^s and feverish night, and continued feverish the next 

 day and night ; after which he was able to drive his team 

 and three horses as usual ; and being inoculated by me with 

 the smal!-pt)x matter, and frequently exposed to the influ- 

 ence of the small-pox in the house of the Smiths, he was 

 found nnstisceptible oj' that disease. 



Olscrration. — Wiiat w^ould have been the consequence 

 of such imprudence under variolous inoculation as was ex- 

 hibited in this case, I leave to the conjecture of the sensible 

 reader ! I'he appearance of a couple of pustules, and these 

 maturating', is a very rare occurrence ; for this disease is 

 ahnost inviiriably confined to the inoculated pustule, and 

 riost probably arose from his blood being over-heated by 

 tiie beer andexcrcise. 



8. Maria Johnson, aet. 16, his sister,, had the cow-pock 

 •without any accompanying fever. 



Observation. — She was inoculated twice for the small- 

 pox, and rubbed her hand over Smith's children, and wa» 

 frequently in the infected house, but was found unsuscepti- 

 ble of that disease. 



Q. William Hodging, set. 13, was inoculated in both 

 arms ; the pustule took, however, only in one. He is car- 

 penter to the earl of Lonsdale, and works with his father 

 in the raft-yard. On the ninth day he had an accession of 

 lever, but not so much as to make him leave oft' work. 



Observations. — This youth lives but two doors from the 

 infected house, was taken by me into this house, and 

 brousht so near to the children as to receive their breath, 

 and at seven different times was inoculated both for tlie 

 5mall-pox, and as many times for the cow-pock ; but iiav- 

 ing had the latter disease, no proper pustule rose, perform- 

 ins its regular stages, or exciting the least constitutionai 

 affection ; and hence he may be safely declared unsuscepti' 

 hie of either disease. 



lb. Mary Henley*, set. 14, was inoculated also in both 



* This case wiih others has led mc to condemn the common practice 

 of inoculating in both arms, or in more than one place, at\d will at Jjst 

 hav« it? cfl'ctt. One point of inocul:uiun i> enough. 



arm?. 



